1 HisKA#1
244-306 aa · 63 aa · 13.5% of protein
Raw token
HisKA:244:0.000000000000644:306:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECSTECEH250_RS02310
Histidine kinase, Classic
Escherichia coli STEC_EH250 · GCF_000225145
ClassHKTypeClassicLength465 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000225145#ECSTECEH250_RS02310Stable P2CS identifier used across views.
GenomeGCF_000225145Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length465 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 465 aa (36.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa465 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
352-458 aa · 107 aa · 23.0% of protein
Raw token
HATPase_c:352:7.94e-34:458:110:109- Raw architecture: HisKA:244:0.000000000000644:306:63:64#HATPase_c:352:7.94e-34:458:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000225145::NZ_AFDW01000037.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25206-27925Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECSTECEH250_4775RefSeq proteinWP_001211892.1
Context group ID
GCF_000225145::NZ_AFDW01000037.1::G00003Context members
ECSTECEH250_RS02310ECSTECEH250_RS02305
Partner locus tags
ECSTECEH250_RS02310ECSTECEH250_RS02305
Partner old locus tags
ECSTECEH250_4775ECSTECEH250_4776
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001211892.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD7FFT5Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD7FFT5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECSTECEH250_RS02310Primary locus identifier stored in the genes table.
Old locus tagECSTECEH250_4775Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AFDW01000037.1Sequence record reported by the local genomic context database.
Genomic interval25 206-26 603 nt1 398 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span25 206-27 925 ntGCF_000225145::NZ_AFDW01000037.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000225145::NZ_AFDW01000037.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFDW01000037.1All displayed genes belong to this local TCS context.
Neighborhood span25 206-27 925 nt2 720 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 206 nt27 925 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECSTECEH250_RS02310GCF_000225145#ECSTECEH250_RS02310
HKClassicCurrent focus
25 206-26 603 nt · Forward (+)
ECSTECEH250_RS02305GCF_000225145#ECSTECEH250_RS02305
RRNtrC
26 600-27 925 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1772879
Simplified PFAM architecture for HKOC_1772879
PFAM domain coverage: 168 / 465 aa (36.1%)
1 aa465 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-307] | HATPase_c[353-457]
- Domain count: 2
- Matched identifier: HKOC_1772879
- Positioned domains: HisKA 245-307 ; HATPase_c 353-457
Cluster members and taxonomy
Representative gene: GCF_000005845#b4003
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 754 087 · GCF_000225145
AssemblyASM22514v2 · Contighaploid
Genome composition5 211 768 bp · 51,0% GCEscherichia coli STEC_EH250
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key