1 HAMP#1
177-246 aa · 70 aa · 14.7% of protein
Raw token
HAMP:177:0.00000000000000611:246:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDM120_RS09330
Histidine kinase, Classic
Clostridioides difficile M120 · GCF_000210435
ClassHKTypeClassicLength477 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210435#CDM120_RS09330Stable P2CS identifier used across views.
GenomeGCF_000210435Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length477 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 477 aa (50.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa477 aa
Domain-by-domain annotation3 items
2 HisKA#2
253-317 aa · 65 aa · 13.6% of protein
Raw token
HisKA:253:9.61e-17:317:65:643 HATPase_c#3
365-470 aa · 106 aa · 22.2% of protein
Raw token
HATPase_c:365:4.1e-27:470:107:109- Raw architecture: HAMP:177:0.00000000000000611:246:70:69#HisKA:253:9.61e-17:317:65:64#HATPase_c:365:4.1e-27:470:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000210435::NC_017174.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1963562-1965696Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000210435::NC_017174.1::G00026Context members
CDM120_RS09325CDM120_RS09330
Partner locus tags
CDM120_RS09325CDM120_RS09330
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003423775.1Primary protein accession used for annex mappings.
UniProt accessionD5Q4X0Primary UniProt accession resolved in the annex database.
UniProt IDD5Q4X0_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDM120_RS09330Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017174.1Sequence record reported by the local genomic context database.
Genomic interval1 964 263-1 965 696 nt1 434 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 963 562-1 965 696 ntGCF_000210435::NC_017174.1::G00026
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000210435::NC_017174.1::G00026Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017174.1All displayed genes belong to this local TCS context.
Neighborhood span1 963 562-1 965 696 nt2 135 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 963 562 nt1 965 696 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDM120_RS09325GCF_000210435#CDM120_RS09325
RROmpR
1 963 562-1 964 260 nt · Forward (+)
CDM120_RS09330GCF_000210435#CDM120_RS09330
HKClassicCurrent focus
1 964 263-1 965 696 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0208845Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1645608
Simplified PFAM architecture for HKOC_1645608
PFAM domain coverage: 220 / 477 aa (46.1%)
1 aa477 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[197-246] | HisKA[253-316] | HATPase_c[365-470]
- Domain count: 3
- Matched identifier: HKOC_1645608
- Positioned domains: HAMP 197-246 ; HisKA 253-316 ; HATPase_c 365-470
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0208845
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 699 035 · GCF_000210435
AssemblyASM21043v1 · Complete Genomehaploid
Genome composition4 047 729 bp · 28,5% GCClostridioides difficile M120
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key