Gene detail

CDM68_RS14020

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS14020Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2071686Run 6 · 257 sequences · id 100% · cov 80% · representative
External referencesWP_003426382.1 · A0A9P4DAK2 · MIST4 CDM68_RS14020RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 440 aa (49.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 156-222 aa (67 aa)1HisKA: 233-291 aa (59 aa)2HATPase_c: 348-439 aa (92 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
156-222 aa · 67 aa · 15.2% of protein
Raw tokenHAMP:156:0.000000000514:222:70:69
2 HisKA#2
233-291 aa · 59 aa · 13.4% of protein
Raw tokenHisKA:233:0.000000000175:291:59:64
3 HATPase_c#3
348-439 aa · 92 aa · 20.9% of protein
Raw tokenHATPase_c:348:0.00000000968:439:108:109
  • Raw architecture: HAMP:156:0.000000000514:222:70:69#HisKA:233:0.000000000175:291:59:64#HATPase_c:348:0.00000000968:439:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3032858-3034877Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00045
Context members
CDM68_RS14020CDM68_RS14025
Partner locus tags
CDM68_RS14020CDM68_RS14025
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426382.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAK2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAK2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS14020Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval3 032 858-3 034 180 nt1 323 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 032 858-3 034 877 ntGCF_000210395::NC_017175.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span3 032 858-3 034 877 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 032 858 nt3 034 877 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS14025GCF_000210395#CDM68_RS14025
RROmpR

3 034 173-3 034 877 nt · Reverse (-)

RefSeq WP_003426384.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2071686Run 6 · HK · 257 sequences
Representative sequenceGCF_000210395#CDM68_RS14020The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2071686

Simplified PFAM architecture for HKOC_2071686

PFAM domain coverage: 175 / 440 aa (39.8%)

1 aa440 aa
HAMP: 177-221 aaHAMPHisKA: 235-291 aaHisKAHATPase_c_5: 364-436 aaHATPase_c_5
HAMPHisKAHATPase_c_5
  • Simplified architecture: HAMP + HisKA + HATPase_c_5
  • Raw architecture: HAMP[177-221] | HisKA[235-291] | HATPase_c_5[364-436]
  • Domain count: 3
  • Matched identifier: HKOC_2071686
  • Positioned domains: HAMP 177-221 ; HisKA 235-291 ; HATPase_c_5 364-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS14020

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 257 total members. Page 1 / 6.

GCF_000210395#CDM68_RS14020 (representative)
CDM68_RS14020 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000210415#CDCF5_RS13995
CDCF5_RS13995 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000235825#HMPREF1122_RS15405
HMPREF1122_RS15405 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000235925#HMPREF1123_RS15650
HMPREF1123_RS15650 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000449945#QIG_RS13570
QIG_RS13570 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000452125#QUY_RS13850
QUY_RS13850 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000452165#QW3_RS14090
QW3_RS14090 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000530915#BN167_RS14060
BN167_RS14060 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_000531625#BN168_RS14070
BN168_RS14070 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_001757585#BW25_RS12315
BW25_RS12315 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_001757625#BW27_RS16410
BW27_RS16410 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_001971875#BER36_RS14720
BER36_RS14720 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_001972195#BER37_RS14365
BER37_RS14365 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002301085#BGU06_RS08445
BGU06_RS08445 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002301635#BGU36_RS02100
BGU36_RS02100 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002302945#BGV12_RS05895
BGV12_RS05895 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002303045#BGV18_RS04540
BGV18_RS04540 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002303155#BGV23_RS10460
BGV23_RS10460 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002303485#BGU64_RS11415
BGU64_RS11415 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002303545#BGU67_RS06435
BGU67_RS06435 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_002940825#AWN77_RS17995
AWN77_RS17995 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003095675#DDG63_RS14925
DDG63_RS14925 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003095695#DDG61_RS14895
DDG61_RS14895 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003324015#DVA89_RS06190
DVA89_RS06190 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003324025#DVA88_RS01225
DVA88_RS01225 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003324035#DVA87_RS09265
DVA87_RS09265 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326835#DVA92_RS00020
DVA92_RS00020 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326845#DVA91_RS16515
DVA91_RS16515 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326875#DVA94_RS06255
DVA94_RS06255 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326885#DVA93_RS16255
DVA93_RS16255 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326915#DVA96_RS00955
DVA96_RS00955 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326935#DVA97_RS00020
DVA97_RS00020 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326945#DVA98_RS11540
DVA98_RS11540 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326965#DVA99_RS00950
DVA99_RS00950 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003326985#DVB00_RS01350
DVB00_RS01350 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327015#DVB04_RS01140
DVB04_RS01140 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327025#DVB06_RS00985
DVB06_RS00985 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327055#DVB02_RS00020
DVB02_RS00020 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327065#DVB01_RS06390
DVB01_RS06390 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327105#DVB12_RS13165
DVB12_RS13165 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327115#DVB09_RS06255
DVB09_RS06255 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327145#DVB10_RS00870
DVB10_RS00870 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327165#DVB07_RS06015
DVB07_RS06015 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327185#DVB14_RS08390
DVB14_RS08390 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327205#DVB16_RS10320
DVB16_RS10320 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327215#DVB15_RS05345
DVB15_RS05345 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327245#DVB19_RS09485
DVB19_RS09485 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327265#DVB18_RS01225
DVB18_RS01225 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327325#DVB05_RS07910
DVB05_RS07910 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2
GCF_003327345#DVB13_RS05955
DVB13_RS05955 · HK · Classic
RefSeq: WP_003426382.1
UniProt: A0A9P4DAK2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key