Gene detail

CDM68_RS13415

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS13415Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440622Run 6 · 285 sequences · id 100% · cov 80% · representative
External referencesWP_003426902.1 · A0A9P3YSF2 · MIST4 CDM68_RS13415RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:1.1e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.0000000011:400:108:109
  • Raw architecture: His_kinase:205:1.1e-31:283:80:80#HATPase_c:300:0.0000000011:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2883393-2885370Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00043
Context members
CDM68_RS13410CDM68_RS13415
Partner locus tags
CDM68_RS13410CDM68_RS13415
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426902.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YSF2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YSF2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS13415Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval2 884 168-2 885 370 nt1 203 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 883 393-2 885 370 ntGCF_000210395::NC_017175.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span2 883 393-2 885 370 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 883 393 nt2 885 370 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS13410GCF_000210395#CDM68_RS13410
RRLytTR

2 883 393-2 884 163 nt · Reverse (-)

RefSeq WP_003426901.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440622Run 6 · HK · 285 sequences
Representative sequenceGCF_000210395#CDM68_RS13415The current gene is the representative for this cluster.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440622

Simplified PFAM architecture for HKOC_2440622

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440622
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS13415

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 285 total members. Page 1 / 6.

GCF_000210395#CDM68_RS13415 (representative)
CDM68_RS13415 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000210415#CDCF5_RS13380
CDCF5_RS13380 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000235825#HMPREF1122_RS14245
HMPREF1122_RS14245 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000235925#HMPREF1123_RS17460
HMPREF1123_RS17460 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000449945#QIG_RS12960
QIG_RS12960 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000452125#QUY_RS13240
QUY_RS13240 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000452165#QW3_RS13480
QW3_RS13480 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000530915#BN167_RS13460
BN167_RS13460 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_000531625#BN168_RS13465
BN168_RS13465 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_001757585#BW25_RS14565
BW25_RS14565 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_001757605#BW28_RS08320
BW28_RS08320 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_001757625#BW27_RS17250
BW27_RS17250 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_001971875#BER36_RS14110
BER36_RS14110 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_001972195#BER37_RS13750
BER37_RS13750 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002301085#BGU06_RS13915
BGU06_RS13915 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002301555#BGU29_RS10335
BGU29_RS10335 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002301635#BGU36_RS13070
BGU36_RS13070 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002302945#BGV12_RS00015
BGV12_RS00015 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002303045#BGV18_RS10635
BGV18_RS10635 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002303155#BGV23_RS15195
BGV23_RS15195 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002303485#BGU64_RS18350
BGU64_RS18350 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_002940825#AWN77_RS05070
AWN77_RS05070 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003095675#DDG63_RS13860
DDG63_RS13860 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003095695#DDG61_RS14280
DDG61_RS14280 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003324015#DVA89_RS15090
DVA89_RS15090 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003324025#DVA88_RS09165
DVA88_RS09165 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003324035#DVA87_RS11635
DVA87_RS11635 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326835#DVA92_RS12235
DVA92_RS12235 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326845#DVA91_RS12555
DVA91_RS12555 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326875#DVA94_RS11170
DVA94_RS11170 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326885#DVA93_RS10710
DVA93_RS10710 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326915#DVA96_RS15180
DVA96_RS15180 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326935#DVA97_RS10315
DVA97_RS10315 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326945#DVA98_RS17220
DVA98_RS17220 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326965#DVA99_RS12135
DVA99_RS12135 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003326985#DVB00_RS15075
DVB00_RS15075 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327015#DVB04_RS18225
DVB04_RS18225 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327025#DVB06_RS14515
DVB06_RS14515 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327055#DVB02_RS07960
DVB02_RS07960 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327065#DVB01_RS14615
DVB01_RS14615 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327105#DVB12_RS14355
DVB12_RS14355 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327115#DVB09_RS11170
DVB09_RS11170 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327145#DVB10_RS15030
DVB10_RS15030 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327165#DVB07_RS14740
DVB07_RS14740 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327185#DVB14_RS13110
DVB14_RS13110 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327205#DVB16_RS18695
DVB16_RS18695 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327215#DVB15_RS10445
DVB15_RS10445 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327245#DVB19_RS09950
DVB19_RS09950 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327265#DVB18_RS09165
DVB18_RS09165 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2
GCF_003327325#DVB05_RS15570
DVB05_RS15570 · HK · Classic
RefSeq: WP_003426902.1
UniProt: A0A9P3YSF2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key