Gene detail

CDM68_RS09595

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength899 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS09595Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0407373Run 6 · 232 sequences · id 100% · cov 80% · representative
External referencesWP_003428621.1 · A0A9P3TYP6 · MIST4 CDM68_RS09595RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length899 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage514 / 899 aa (57.2%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for CDM68_RS09595
Domain-by-domain annotation4 items
1 KdpD#1
22-230 aa · 209 aa · 23.2% of protein
Raw tokenKdpD:22:4.34e-134:230:209:210
2 GAF_3#2
533-656 aa · 124 aa · 13.8% of protein
Raw tokenGAF_3:533:0.00000107:656:129:129
3 HisKA#3
676-743 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:676:0.0000000000036:743:68:64
4 HATPase_c#4
787-899 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:787:1.61e-30:899:113:109
  • Raw architecture: KdpD:22:4.34e-134:230:209:210#GAF_3:533:0.00000107:656:129:129#HisKA:676:0.0000000000036:743:68:64#HATPase_c:787:1.61e-30:899:113:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2041998-2045432Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00031
Context members
CDM68_RS09595CDM68_RS09600
Partner locus tags
CDM68_RS09595CDM68_RS09600
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003428621.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3TYP6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3TYP6_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS09595Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval2 041 998-2 044 697 nt2 700 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 041 998-2 045 432 ntGCF_000210395::NC_017175.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span2 041 998-2 045 432 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 041 998 nt2 045 432 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS09600GCF_000210395#CDM68_RS09600
RROmpR

2 044 734-2 045 432 nt · Forward (+)

RefSeq WP_003428622.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0407373Run 6 · HK · 232 sequences
Representative sequenceGCF_000210395#CDM68_RS09595The current gene is the representative for this cluster.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0407373

Simplified PFAM architecture for HKOC_0407373

PFAM domain coverage: 494 / 899 aa (54.9%)

1 aa899 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0407373
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS09595

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key