Gene detail

CDM68_RS05070

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS05070Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504334Run 6 · 274 sequences · id 100% · cov 80% · representative
External referencesWP_003432175.1 · A0A9P3YS97 · MIST4 CDM68_RS05070RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000523:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:4.11e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:2.38e-27:495:106:109
  • Raw architecture: HAMP:212:0.00000523:279:68:69#HisKA:289:4.11e-17:347:59:64#HATPase_c:395:2.38e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1078399-1080592Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00017
Context members
CDM68_RS05065CDM68_RS05070
Partner locus tags
CDM68_RS05065CDM68_RS05070
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003432175.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YS97Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YS97_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS05070Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval1 079 105-1 080 592 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 078 399-1 080 592 ntGCF_000210395::NC_017175.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span1 078 399-1 080 592 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 078 399 nt1 080 592 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS05065GCF_000210395#CDM68_RS05065
RROmpR

1 078 399-1 079 103 nt · Forward (+)

RefSeq WP_003432177.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504334Run 6 · HK · 274 sequences
Representative sequenceGCF_000210395#CDM68_RS05070The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504334

Simplified PFAM architecture for HKOC_1504334

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504334
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS05070

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 274 total members. Page 1 / 6.

GCF_000210395#CDM68_RS05070 (representative)
CDM68_RS05070 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000210415#CDCF5_RS05095
CDCF5_RS05095 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000235825#HMPREF1122_RS11200
HMPREF1122_RS11200 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000235925#HMPREF1123_RS13565
HMPREF1123_RS13565 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000449945#QIG_RS04745
QIG_RS04745 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000452125#QUY_RS04735
QUY_RS04735 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000452165#QW3_RS04655
QW3_RS04655 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_000530915#BN167_RS05090
BN167_RS05090 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_001757585#BW25_RS11970
BW25_RS11970 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_001757605#BW28_RS00980
BW28_RS00980 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_001757625#BW27_RS08415
BW27_RS08415 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_001971875#BER36_RS05545
BER36_RS05545 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_001972195#BER37_RS05340
BER37_RS05340 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002301085#BGU06_RS06060
BGU06_RS06060 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002301435#BGU22_RS13905
BGU22_RS13905 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002301555#BGU29_RS02820
BGU29_RS02820 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002301635#BGU36_RS15520
BGU36_RS15520 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002302945#BGV12_RS02925
BGV12_RS02925 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002303045#BGV18_RS01250
BGV18_RS01250 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002303155#BGV23_RS11270
BGV23_RS11270 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002303485#BGU64_RS18820
BGU64_RS18820 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002303545#BGU67_RS08590
BGU67_RS08590 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_002940825#AWN77_RS10875
AWN77_RS10875 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003095675#DDG63_RS05530
DDG63_RS05530 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003095695#DDG61_RS05800
DDG61_RS05800 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003324015#DVA89_RS13865
DVA89_RS13865 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003324025#DVA88_RS12270
DVA88_RS12270 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003324035#DVA87_RS15950
DVA87_RS15950 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326835#DVA92_RS14290
DVA92_RS14290 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326845#DVA91_RS00110
DVA91_RS00110 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326875#DVA94_RS07510
DVA94_RS07510 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326885#DVA93_RS15370
DVA93_RS15370 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326915#DVA96_RS14390
DVA96_RS14390 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326935#DVA97_RS07165
DVA97_RS07165 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326945#DVA98_RS04290
DVA98_RS04290 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326965#DVA99_RS05905
DVA99_RS05905 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003326985#DVB00_RS15685
DVB00_RS15685 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327015#DVB04_RS13800
DVB04_RS13800 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327025#DVB06_RS15840
DVB06_RS15840 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327055#DVB02_RS16080
DVB02_RS16080 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327065#DVB01_RS12945
DVB01_RS12945 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327105#DVB12_RS15200
DVB12_RS15200 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327115#DVB09_RS07510
DVB09_RS07510 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327145#DVB10_RS16655
DVB10_RS16655 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327165#DVB07_RS16705
DVB07_RS16705 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327185#DVB14_RS12535
DVB14_RS12535 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327205#DVB16_RS08140
DVB16_RS08140 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327215#DVB15_RS13770
DVB15_RS13770 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327265#DVB18_RS12270
DVB18_RS12270 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97
GCF_003327325#DVB05_RS14620
DVB05_RS14620 · HK · Classic
RefSeq: WP_003432175.1
UniProt: A0A9P3YS97

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key