Gene detail

CDM68_RS03685

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS03685Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737723Run 6 · 242 sequences · id 100% · cov 80% · representative
External referencesWP_021387636.1 · A0A9P4DAW6 · MIST4 CDM68_RS03685RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
HisKA: 245-309 aa (65 aa)1HATPase_c: 357-466 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.00000000000164:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:9.96e-19:466:111:109
  • Raw architecture: HisKA:245:0.00000000000164:309:65:64#HATPase_c:357:9.96e-19:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span755053-757211Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00014
Context members
CDM68_RS03680CDM68_RS03685
Partner locus tags
CDM68_RS03680CDM68_RS03685
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021387636.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAW6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAW6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS03685Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval755 805-757 211 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span755 053-757 211 ntGCF_000210395::NC_017175.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span755 053-757 211 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
755 053 nt757 211 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS03680GCF_000210395#CDM68_RS03680
RROmpR

755 053-755 760 nt · Forward (+)

RefSeq WP_021387635.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737723Run 6 · HK · 242 sequences
Representative sequenceGCF_000210395#CDM68_RS03685The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737723

Simplified PFAM architecture for HKOC_1737723

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737723
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS03685

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 242 total members. Page 1 / 5.

GCF_000210395#CDM68_RS03685 (representative)
CDM68_RS03685 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000210415#CDCF5_RS03740
CDCF5_RS03740 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000235825#HMPREF1122_RS14325
HMPREF1122_RS14325 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000235925#HMPREF1123_RS14305
HMPREF1123_RS14305 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000449945#QIG_RS03285
QIG_RS03285 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000452125#QUY_RS03370
QUY_RS03370 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000452165#QW3_RS03280
QW3_RS03280 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000530915#BN167_RS03695
BN167_RS03695 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_000531625#BN168_RS03645
BN168_RS03645 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_001971875#BER36_RS04150
BER36_RS04150 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_001972195#BER37_RS03950
BER37_RS03950 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002301085#BGU06_RS15715
BGU06_RS15715 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002301435#BGU22_RS16370
BGU22_RS16370 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002301555#BGU29_RS13230
BGU29_RS13230 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002301635#BGU36_RS17410
BGU36_RS17410 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002302945#BGV12_RS14265
BGV12_RS14265 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002303045#BGV18_RS17050
BGV18_RS17050 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002303155#BGV23_RS16705
BGV23_RS16705 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002303485#BGU64_RS17765
BGU64_RS17765 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002303545#BGU67_RS17165
BGU67_RS17165 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_002940825#AWN77_RS20170
AWN77_RS20170 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003095675#DDG63_RS04125
DDG63_RS04125 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003095695#DDG61_RS04340
DDG61_RS04340 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003324015#DVA89_RS14515
DVA89_RS14515 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003324025#DVA88_RS15020
DVA88_RS15020 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003324035#DVA87_RS18110
DVA87_RS18110 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326835#DVA92_RS18265
DVA92_RS18265 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326845#DVA91_RS15435
DVA91_RS15435 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326875#DVA94_RS15290
DVA94_RS15290 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326885#DVA93_RS18410
DVA93_RS18410 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326915#DVA96_RS18140
DVA96_RS18140 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326935#DVA97_RS15905
DVA97_RS15905 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326945#DVA98_RS18305
DVA98_RS18305 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326965#DVA99_RS18245
DVA99_RS18245 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003326985#DVB00_RS16335
DVB00_RS16335 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327015#DVB04_RS16330
DVB04_RS16330 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327025#DVB06_RS14905
DVB06_RS14905 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327055#DVB02_RS15485
DVB02_RS15485 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327065#DVB01_RS19840
DVB01_RS19840 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327105#DVB12_RS19755
DVB12_RS19755 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327115#DVB09_RS15290
DVB09_RS15290 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327145#DVB10_RS13335
DVB10_RS13335 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327165#DVB07_RS17685
DVB07_RS17685 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327185#DVB14_RS19375
DVB14_RS19375 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327205#DVB16_RS19485
DVB16_RS19485 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327215#DVB15_RS17020
DVB15_RS17020 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327245#DVB19_RS19290
DVB19_RS19290 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327265#DVB18_RS15020
DVB18_RS15020 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327325#DVB05_RS19870
DVB05_RS19870 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6
GCF_003327345#DVB13_RS20125
DVB13_RS20125 · HK · Classic
RefSeq: WP_021387636.1
UniProt: A0A9P4DAW6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key