Gene detail

CDM68_RS02680

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS02680Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674287Run 6 · 220 sequences · id 100% · cov 80% · representative
External referencesWP_003426340.1 · A0A9P3TX80 · MIST4 CDM68_RS02680RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000158:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000176:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:3.28e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000158:238:78:69#HisKA:250:0.00000000176:315:66:64#HATPase_c:365:3.28e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span513437-515572Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00005
Context members
CDM68_RS02675CDM68_RS02680
Partner locus tags
CDM68_RS02675CDM68_RS02680
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426340.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3TX80Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3TX80_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS02680Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval514 148-515 572 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span513 437-515 572 ntGCF_000210395::NC_017175.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span513 437-515 572 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
513 437 nt515 572 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS02675GCF_000210395#CDM68_RS02675
RROmpR

513 437-514 129 nt · Forward (+)

RefSeq WP_003426338.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674287Run 6 · HK · 220 sequences
Representative sequenceGCF_000210395#CDM68_RS02680The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674287

Simplified PFAM architecture for HKOC_1674287

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674287
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS02680

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 220 total members. Page 1 / 5.

GCF_000210395#CDM68_RS02680 (representative)
CDM68_RS02680 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000210415#CDCF5_RS02735
CDCF5_RS02735 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000235825#HMPREF1122_RS15495
HMPREF1122_RS15495 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000235925#HMPREF1123_RS13750
HMPREF1123_RS13750 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000449945#QIG_RS02280
QIG_RS02280 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000452125#QUY_RS02365
QUY_RS02365 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000452165#QW3_RS09575
QW3_RS09575 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_000530915#BN167_RS02695
BN167_RS02695 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_001757605#BW28_RS00340
BW28_RS00340 · HK · Classic
RefSeq: WP_330388657.1
GCF_001971875#BER36_RS03115
BER36_RS03115 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_001972195#BER37_RS02915
BER37_RS02915 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002301085#BGU06_RS16300
BGU06_RS16300 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002301435#BGU22_RS10865
BGU22_RS10865 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002301555#BGU29_RS15780
BGU29_RS15780 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002301635#BGU36_RS09155
BGU36_RS09155 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002302945#BGV12_RS01420
BGV12_RS01420 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002303045#BGV18_RS14485
BGV18_RS14485 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002303155#BGV23_RS12610
BGV23_RS12610 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002303485#BGU64_RS01755
BGU64_RS01755 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_002940825#AWN77_RS01950
AWN77_RS01950 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003095675#DDG63_RS03090
DDG63_RS03090 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003095695#DDG61_RS03305
DDG61_RS03305 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003324015#DVA89_RS00085
DVA89_RS00085 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003324025#DVA88_RS16065
DVA88_RS16065 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003324035#DVA87_RS12865
DVA87_RS12865 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326835#DVA92_RS15135
DVA92_RS15135 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326845#DVA91_RS13300
DVA91_RS13300 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326875#DVA94_RS14740
DVA94_RS14740 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326885#DVA93_RS15910
DVA93_RS15910 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326915#DVA96_RS13135
DVA96_RS13135 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326935#DVA97_RS14545
DVA97_RS14545 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326945#DVA98_RS07670
DVA98_RS07670 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326965#DVA99_RS01485
DVA99_RS01485 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003326985#DVB00_RS13410
DVB00_RS13410 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327015#DVB04_RS12305
DVB04_RS12305 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327025#DVB06_RS12605
DVB06_RS12605 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327055#DVB02_RS08965
DVB02_RS08965 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327105#DVB12_RS05715
DVB12_RS05715 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327115#DVB09_RS14740
DVB09_RS14740 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327165#DVB07_RS12645
DVB07_RS12645 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327185#DVB14_RS06080
DVB14_RS06080 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327205#DVB16_RS08655
DVB16_RS08655 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327215#DVB15_RS11825
DVB15_RS11825 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327245#DVB19_RS06975
DVB19_RS06975 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327265#DVB18_RS16065
DVB18_RS16065 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003327325#DVB05_RS09965
DVB05_RS09965 · HK · Classic
RefSeq: WP_330388657.1
GCF_003327345#DVB13_RS10180
DVB13_RS10180 · HK · Classic
RefSeq: WP_330388657.1
GCF_003327755#DVB17_RS04180
DVB17_RS04180 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003328455#DR993_RS14700
DR993_RS14700 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80
GCF_003482125#CDIF28669_RS02765
CDIF28669_RS02765 · HK · Classic
RefSeq: WP_003426340.1
UniProt: A0A9P3TX80

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key