Gene detail

ECB41_RS08555

Histidine kinase, Unorthodox

Escherichia coli B41 · GCF_000194705

ClassHKTypeUnorthodoxLength778 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000194705#ECB41_RS08555Stable P2CS identifier used across views.
GenomeGCF_000194705Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_0597533Run 6 · 29185 sequences · id 100% · cov 80%
External referencesWP_000809774.1 · A0A8E0FMX1 · MIST4 ECB41_RS08555RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_cResponse_regHpt
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage474 / 778 aa (60.9%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa778 aa
PAS: 156-266 aa (111 aa)1HisKA: 283-345 aa (63 aa)2HATPase_c: 394-506 aa (113 aa)3Response_reg: 528-640 aa (113 aa)4Hpt: 686-759 aa (74 aa)5
Domain-by-domain annotation5 items
1 PAS#1
156-266 aa · 111 aa · 14.3% of protein
Raw tokenPAS:156:1.74e-19:266:112:113
2 HisKA#2
283-345 aa · 63 aa · 8.1% of protein
Raw tokenHisKA:283:0.00000000000000103:345:63:64
3 HATPase_c#3
394-506 aa · 113 aa · 14.5% of protein
Raw tokenHATPase_c:394:7.51e-37:506:113:109
4 Response_reg#4
528-640 aa · 113 aa · 14.5% of protein
Raw tokenResponse_reg:528:2.23e-28:640:114:111
5 Hpt#5
686-759 aa · 74 aa · 9.5% of protein
Raw tokenHpt:686:0.00000000000817:759:78:84
  • Raw architecture: PAS:156:1.74e-19:266:112:113#HisKA:283:0.00000000000000103:345:63:64#HATPase_c:394:7.51e-37:506:113:109#Response_reg:528:2.23e-28:640:114:111#Hpt:686:0.00000000000817:759:78:84
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000194705::NZ_AFAH02000003.1::G00029
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1981711-1984047Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECB41_3602RefSeq proteinWP_000809774.1
Context group IDGCF_000194705::NZ_AFAH02000003.1::G00029
Context members
ECB41_RS08555
Partner locus tags
ECB41_RS08555
Partner old locus tags
ECB41_3602
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000809774.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FMX1Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FMX1_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECB41_RS08555Primary locus identifier stored in the genes table.
Old locus tagECB41_3602Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AFAH02000003.1Sequence record reported by the local genomic context database.
Genomic interval1 981 711-1 984 047 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 981 711-1 984 047 ntGCF_000194705::NZ_AFAH02000003.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000194705::NZ_AFAH02000003.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFAH02000003.1All displayed genes belong to this local TCS context.
Neighborhood span1 981 711-1 984 047 nt2 337 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 981 711 nt1 984 047 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

ECB41_RS08555GCF_000194705#ECB41_RS08555
HKUnorthodoxCurrent focus

1 981 711-1 984 047 nt · Reverse (-)

Old locus ECB41_3602RefSeq WP_000809774.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0597533Run 6 · HK · 29185 sequences
Representative sequenceGCF_022494435#HZT08_RS02540Use this link to inspect the representative gene detail.
PFAM architectureHKR_ArcB_TM + PAS + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0597533

Simplified PFAM architecture for HKOC_0597533

PFAM domain coverage: 547 / 779 aa (70.2%)

1 aa779 aa
HKR_ArcB_TM: 15-88 aaHKR_ArcB_TMPAS: 156-266 aaPASHisKA: 283-345 aaHisKAHATPase_c: 395-505 aaHATPase_cResponse_reg: 528-640 aaResponse_regHpt: 686-760 aaHpt
HKR_ArcB_TMPASHisKAHATPase_cResponse_regHpt
  • Simplified architecture: HKR_ArcB_TM + PAS + HisKA + HATPase_c + Response_reg + Hpt
  • Raw architecture: HKR_ArcB_TM[15-88] | PAS[156-266] | HisKA[283-345] | HATPase_c[395-505] | Response_reg[528-640] | Hpt[686-760]
  • Domain count: 6
  • Matched identifier: HKOC_0597533
  • Positioned domains: HKR_ArcB_TM 15-88 ; PAS 156-266 ; HisKA 283-345 ; HATPase_c 395-505 ; Response_reg 528-640 ; Hpt 686-760
Cluster members and taxonomy
Visualization

Representative gene: GCF_022494435#HZT08_RS02540

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 869 694 · GCF_000194705
AssemblyASM19470v2 · Contighaploid
Genome composition5 011 605 bp · 50,5% GCEscherichia coli B41
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key