Gene detail

ECB41_RS02205

Histidine kinase, Classic

Escherichia coli B41 · GCF_000194705

ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000194705#ECB41_RS02205Stable P2CS identifier used across views.
GenomeGCF_000194705Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2711914Run 6 · 8199 sequences · id 100% · cov 80%
External referencesWP_001051092.1 · A0AAN3ZJ87 · MIST4 ECB41_RS02205RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
HAMP: 72-139 aa (68 aa)1HisKA: 147-204 aa (58 aa)2HATPase_c: 252-360 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw tokenHAMP:72:0.000000781:139:68:69
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw tokenHisKA:147:0.00000000177:204:61:64
3 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw tokenHATPase_c:252:5.06e-22:360:111:109
  • Raw architecture: HAMP:72:0.000000781:139:68:69#HisKA:147:0.00000000177:204:61:64#HATPase_c:252:5.06e-22:360:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000194705::NZ_AFAH02000005.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span553300-555069Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECB41_4573RefSeq proteinWP_001051092.1
Context group IDGCF_000194705::NZ_AFAH02000005.1::G00005
Context members
ECB41_RS02205ECB41_RS02200
Partner locus tags
ECB41_RS02205ECB41_RS02200
Partner old locus tags
ECB41_4573ECB41_4574
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001051092.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN3ZJ87Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN3ZJ87_SHIDYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECB41_RS02205Primary locus identifier stored in the genes table.
Old locus tagECB41_4573Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AFAH02000005.1Sequence record reported by the local genomic context database.
Genomic interval553 300-554 400 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span553 300-555 069 ntGCF_000194705::NZ_AFAH02000005.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000194705::NZ_AFAH02000005.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFAH02000005.1All displayed genes belong to this local TCS context.
Neighborhood span553 300-555 069 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
553 300 nt555 069 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECB41_RS02205GCF_000194705#ECB41_RS02205
HKClassicCurrent focus

553 300-554 400 nt · Reverse (-)

Old locus ECB41_4573RefSeq WP_001051092.1
ECB41_RS02200GCF_000194705#ECB41_RS02200
RROmpR

554 401-555 069 nt · Reverse (-)

Old locus ECB41_4574RefSeq WP_000697915.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2711914Run 6 · HK · 8199 sequences
Representative sequenceGCF_000010245#Y75_RS21455Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2711914

Simplified PFAM architecture for HKOC_2711914

PFAM domain coverage: 165 / 366 aa (45.1%)

1 aa366 aa
HisKA: 147-203 aaHisKAHATPase_c: 252-359 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[147-203] | HATPase_c[252-359]
  • Domain count: 2
  • Matched identifier: HKOC_2711914
  • Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Visualization

Representative gene: GCF_000010245#Y75_RS21455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 869 694 · GCF_000194705
AssemblyASM19470v2 · Contighaploid
Genome composition5 011 605 bp · 50,5% GCEscherichia coli B41
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key