Gene detail

ECB41_RS00715

Histidine kinase, Classic

Escherichia coli B41 · GCF_000194705

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000194705#ECB41_RS00715Stable P2CS identifier used across views.
GenomeGCF_000194705Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1674260Run 6 · 1461 sequences · id 100% · cov 80%
External referencesWP_001219615.1 · A0ABD5BWQ2 · MIST4 ECB41_RS00715RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 474 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 184-251 aa (68 aa)1HisKA: 257-319 aa (63 aa)2HATPase_c: 365-469 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
184-251 aa · 68 aa · 14.3% of protein
Raw tokenHAMP:184:0.000000000251:251:68:69
2 HisKA#2
257-319 aa · 63 aa · 13.3% of protein
Raw tokenHisKA:257:0.00000000000322:319:63:64
3 HATPase_c#3
365-469 aa · 105 aa · 22.2% of protein
Raw tokenHATPase_c:365:8.4e-24:469:105:109
  • Raw architecture: HAMP:184:0.000000000251:251:68:69#HisKA:257:0.00000000000322:319:63:64#HATPase_c:365:8.4e-24:469:105:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000194705::NZ_AFAH02000005.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span867477-869590Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECB41_4898RefSeq proteinWP_001219615.1
Context group IDGCF_000194705::NZ_AFAH02000005.1::G00007
Context members
ECB41_RS00720ECB41_RS00715
Partner locus tags
ECB41_RS00720ECB41_RS00715
Partner old locus tags
ECB41_4897ECB41_4898
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001219615.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD5BWQ2Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD5BWQ2_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECB41_RS00715Primary locus identifier stored in the genes table.
Old locus tagECB41_4898Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AFAH02000005.1Sequence record reported by the local genomic context database.
Genomic interval868 166-869 590 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span867 477-869 590 ntGCF_000194705::NZ_AFAH02000005.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000194705::NZ_AFAH02000005.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFAH02000005.1All displayed genes belong to this local TCS context.
Neighborhood span867 477-869 590 nt2 114 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
867 477 nt869 590 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECB41_RS00720GCF_000194705#ECB41_RS00720
RROmpR

867 477-868 166 nt · Forward (+)

Old locus ECB41_4897RefSeq WP_001188664.1
ECB41_RS00715GCF_000194705#ECB41_RS00715
HKClassicCurrent focus

868 166-869 590 nt · Forward (+)

Old locus ECB41_4898RefSeq WP_001219615.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674260Run 6 · HK · 1461 sequences
Representative sequenceGCF_000190835#ERDG_RS04470Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674260

Simplified PFAM architecture for HKOC_1674260

PFAM domain coverage: 217 / 474 aa (45.8%)

1 aa474 aa
HAMP: 202-251 aaHAMPHisKA: 258-319 aaHisKAHATPase_c: 365-469 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[202-251] | HisKA[258-319] | HATPase_c[365-469]
  • Domain count: 3
  • Matched identifier: HKOC_1674260
  • Positioned domains: HAMP 202-251 ; HisKA 258-319 ; HATPase_c 365-469
Cluster members and taxonomy
Visualization

Representative gene: GCF_000190835#ERDG_RS04470

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 869 694 · GCF_000194705
AssemblyASM19470v2 · Contighaploid
Genome composition5 011 605 bp · 50,5% GCEscherichia coli B41
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key