1 Response_reg#1
8-118 aa · 111 aa · 25.2% of protein
Raw token
Response_reg:8:2.51e-38:118:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ERGG_RS00420
Response regulator NtrC family
Escherichia coli H489 · GCF_000191015
ClassRRTypeNtrCLength441 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000191015#ERGG_RS00420Stable P2CS identifier used across views.
GenomeGCF_000191015Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regAAA_5HTH_8
Protein length441 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage268 / 441 aa (60.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa441 aa
Domain-by-domain annotation3 items
2 AAA_5#2
165-283 aa · 119 aa · 27.0% of protein
Raw token
AAA_5:165:0.00000000678:283:124:1353 HTH_8#3
404-441 aa · 38 aa · 8.6% of protein
Raw token
HTH_8:404:0.0000000000000194:441:38:40- Raw architecture: Response_reg:8:2.51e-38:118:111:111#AAA_5:165:0.00000000678:283:124:135#HTH_8:404:0.0000000000000194:441:38:40
- Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000191015::NZ_GL872259.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30578-33276Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERGG_04561RefSeq proteinWP_000148551.1
Context group ID
GCF_000191015::NZ_GL872259.1::G00038Context members
ERGG_RS00425ERGG_RS00420
Partner locus tags
ERGG_RS00425ERGG_RS00420
Partner old locus tags
ERGG_04560ERGG_04561
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000148551.1Primary protein accession used for annex mappings.
UniProt accessionW8SY10Primary UniProt accession resolved in the annex database.
UniProt IDW8SY10_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 2Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagERGG_RS00420Primary locus identifier stored in the genes table.
Old locus tagERGG_04561Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL872259.1Sequence record reported by the local genomic context database.
Genomic interval31 951-33 276 nt1 326 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 578-33 276 ntGCF_000191015::NZ_GL872259.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000191015::NZ_GL872259.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL872259.1All displayed genes belong to this local TCS context.
Neighborhood span30 578-33 276 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 578 nt33 276 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ERGG_RS00425GCF_000191015#ERGG_RS00425
HKClassic
30 578-31 954 nt · Forward (+)
ERGG_RS00420GCF_000191015#ERGG_RS00420
RRNtrCCurrent focus
31 951-33 276 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009565#B21_RS20385Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.
PFAM architecture for RROC_0329711
Simplified PFAM architecture for RROC_0329711
PFAM domain coverage: 393 / 441 aa (89.1%)
1 aa441 aa
Response_regSigma54_activatAAA_lid_14HTH_8
- Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
- Raw architecture: Response_reg[8-117] | Sigma54_activat[141-308] | AAA_lid_14[313-389] | HTH_8[403-440]
- Domain count: 4
- Matched identifier: RROC_0329711
- Positioned domains: Response_reg 8-117 ; Response_reg 8-117 ; Sigma54_activat 141-308 ; Sigma54_activat 141-308 ; AAA_lid_14 313-389 ; AAA_lid_14 313-389 ; HTH_8 403-440 ; HTH_8 403-440
Cluster members and taxonomy
Representative gene: GCF_000009565#B21_RS20385
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 656 404 · GCF_000191015
AssemblyASM19101v1 · Scaffoldhaploid
Genome composition4 876 591 bp · 51,0% GCEscherichia coli H489
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key