1 HisKA_3#1
175-243 aa · 69 aa · 18.9% of protein
Raw token
HisKA_3:175:4.16e-18:243:69:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SPN7465_RS11110
Histidine kinase, Classic
Streptococcus pneumoniae SPN7465 · GCF_000180495
ClassHKTypeClassicLength365 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000180495#SPN7465_RS11110Stable P2CS identifier used across views.
GenomeGCF_000180495Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length365 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage150 / 365 aa (41.1%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa365 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
283-363 aa · 81 aa · 22.2% of protein
Raw token
HATPase_c:283:0.00000000016:363:101:109- Raw architecture: HisKA_3:175:4.16e-18:243:69:68#HATPase_c:283:0.00000000016:363:101:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000180495::NZ_CACF01000021.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3115-4813Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000180495::NZ_CACF01000021.1::G00001Context members
SPN7465_RS11110SPN7465_RS11115
Partner locus tags
SPN7465_RS11110SPN7465_RS11115
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000893532.1Primary protein accession used for annex mappings.
UniProt accessionA0A5Q5G5I4Primary UniProt accession resolved in the annex database.
UniProt IDA0A5Q5G5I4_STREEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSPN7465_RS11110Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CACF01000021.1Sequence record reported by the local genomic context database.
Genomic interval3 115-4 212 nt1 098 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 115-4 813 ntGCF_000180495::NZ_CACF01000021.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000180495::NZ_CACF01000021.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CACF01000021.1All displayed genes belong to this local TCS context.
Neighborhood span3 115-4 813 nt1 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 115 nt4 813 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SPN7465_RS11110GCF_000180495#SPN7465_RS11110
HKClassicCurrent focus
3 115-4 212 nt · Forward (+)
SPN7465_RS11115GCF_000180495#SPN7465_RS11115
RRNarL
4 214-4 813 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000180495#SPN7465_RS11110The current gene is the representative for this cluster.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2718334
Simplified PFAM architecture for HKOC_2718334
PFAM domain coverage: 110 / 365 aa (30.1%)
1 aa365 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[175-242] | HATPase_c[282-323]
- Domain count: 2
- Matched identifier: HKOC_2718334
- Positioned domains: HisKA_3 175-242 ; HATPase_c 282-323
Cluster members and taxonomy
Representative gene: GCF_000180495#SPN7465_RS11110
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 869 313 · GCF_000180495
AssemblyASM18049v1 · Contighaploid
Genome composition2 084 938 bp · 39,5% GCStreptococcus pneumoniae SPN7465
Signal transduction countsGenes 27 · HK 13 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key