Gene detail

SPN7465_RS06525

Histidine kinase, Classic

Streptococcus pneumoniae SPN7465 · GCF_000180495

ClassHKTypeClassicLength350 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000180495#SPN7465_RS06525Stable P2CS identifier used across views.
GenomeGCF_000180495Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_2796907Run 6 · 5685 sequences · id 100% · cov 80%
External referencesWP_000769768.1 · Q8DRK0 · MIST4 SPN7465_RS06525RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length350 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 350 aa (69.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa350 aa
HAMP: 39-107 aa (69 aa)1HisKA: 119-180 aa (62 aa)2HATPase_c: 233-343 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
39-107 aa · 69 aa · 19.7% of protein
Raw tokenHAMP:39:0.000000000105:107:69:69
2 HisKA#2
119-180 aa · 62 aa · 17.7% of protein
Raw tokenHisKA:119:0.0000000000013:180:62:64
3 HATPase_c#3
233-343 aa · 111 aa · 31.7% of protein
Raw tokenHATPase_c:233:1.64e-32:343:111:109
  • Raw architecture: HAMP:39:0.000000000105:107:69:69#HisKA:119:0.0000000000013:180:62:64#HATPase_c:233:1.64e-32:343:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000180495::NZ_CACF01000002.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span349226-350973Genomic interval covered by the local TCS group.
Context group IDGCF_000180495::NZ_CACF01000002.1::G00009
Context members
SPN7465_RS06525SPN7465_RS06530
Partner locus tags
SPN7465_RS06525SPN7465_RS06530
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000769768.1Primary protein accession used for annex mappings.
UniProt accessionQ8DRK0Primary UniProt accession resolved in the annex database.
UniProt IDQ8DRK0_STRR6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSPN7465_RS06525Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CACF01000002.1Sequence record reported by the local genomic context database.
Genomic interval349 226-350 278 nt1 053 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span349 226-350 973 ntGCF_000180495::NZ_CACF01000002.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000180495::NZ_CACF01000002.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CACF01000002.1All displayed genes belong to this local TCS context.
Neighborhood span349 226-350 973 nt1 748 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
349 226 nt350 973 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2796907Run 6 · HK · 5685 sequences
Representative sequenceGCF_000006885#SP_RS00435Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2796907

Simplified PFAM architecture for HKOC_2796907

PFAM domain coverage: 216 / 350 aa (61.7%)

1 aa350 aa
HAMP: 63-107 aaHAMPHisKA: 120-179 aaHisKAHATPase_c: 233-343 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[63-107] | HisKA[120-179] | HATPase_c[233-343]
  • Domain count: 3
  • Matched identifier: HKOC_2796907
  • Positioned domains: HAMP 63-107 ; HisKA 120-179 ; HATPase_c 233-343
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006885#SP_RS00435

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 869 313 · GCF_000180495
AssemblyASM18049v1 · Contighaploid
Genome composition2 084 938 bp · 39,5% GCStreptococcus pneumoniae SPN7465
Signal transduction countsGenes 27 · HK 13 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key