1 PAS_9#1
104-201 aa · 98 aa · 21.8% of protein
Raw token
PAS_9:104:0.00000000000641:201:102:102P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SPN7465_RS03355
Histidine kinase, Classic
Streptococcus pneumoniae SPN7465 · GCF_000180495
ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000180495#SPN7465_RS03355Stable P2CS identifier used across views.
GenomeGCF_000180495Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
PAS_9HisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage276 / 449 aa (61.5%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
Domain-by-domain annotation3 items
2 HisKA#2
208-273 aa · 66 aa · 14.7% of protein
Raw token
HisKA:208:0.0000000000000014:273:66:643 HATPase_c#3
324-435 aa · 112 aa · 24.9% of protein
Raw token
HATPase_c:324:1.62e-34:435:112:109- Raw architecture: PAS_9:104:0.00000000000641:201:102:102#HisKA:208:0.0000000000000014:273:66:64#HATPase_c:324:1.62e-34:435:112:109
- Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000180495::NZ_CACF01000001.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span648335-650381Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000180495::NZ_CACF01000001.1::G00014Context members
SPN7465_RS03355SPN7465_RS03360
Partner locus tags
SPN7465_RS03355SPN7465_RS03360
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000886210.1Primary protein accession used for annex mappings.
UniProt accessionC1C7J1Primary UniProt accession resolved in the annex database.
UniProt IDC1C7J1_STRP7Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSPN7465_RS03355Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CACF01000001.1Sequence record reported by the local genomic context database.
Genomic interval648 335-649 684 nt1 350 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span648 335-650 381 ntGCF_000180495::NZ_CACF01000001.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000180495::NZ_CACF01000001.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CACF01000001.1All displayed genes belong to this local TCS context.
Neighborhood span648 335-650 381 nt2 047 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
648 335 nt650 381 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SPN7465_RS03355GCF_000180495#SPN7465_RS03355
HKClassicCurrent focus
648 335-649 684 nt · Reverse (-)
SPN7465_RS03360GCF_000180495#SPN7465_RS03360
RROmpR
649 677-650 381 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_900023315#A1O87_RS07975Use this link to inspect the representative gene detail.
PFAM architectureCovS-like_HAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1948768
Simplified PFAM architecture for HKOC_1948768
PFAM domain coverage: 334 / 452 aa (73.9%)
1 aa452 aa
CovS-like_HAMPPASHisKAHATPase_c
- Simplified architecture: CovS-like_HAMP + PAS + HisKA + HATPase_c
- Raw architecture: CovS-like_HAMP[32-87] | PAS[97-198] | HisKA[209-273] | HATPase_c[324-434]
- Domain count: 4
- Matched identifier: HKOC_1948768
- Positioned domains: CovS-like_HAMP 32-87 ; PAS 97-198 ; HisKA 209-273 ; HATPase_c 324-434
Cluster members and taxonomy
Representative gene: GCF_900023315#A1O87_RS07975
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 869 313 · GCF_000180495
AssemblyASM18049v1 · Contighaploid
Genome composition2 084 938 bp · 39,5% GCStreptococcus pneumoniae SPN7465
Signal transduction countsGenes 27 · HK 13 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key