1 HisKA#1
216-283 aa · 68 aa · 15.3% of protein
Raw token
HisKA:216:0.000000000045:283:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SPN7465_RS01325
Histidine kinase, Classic
Streptococcus pneumoniae SPN7465 · GCF_000180495
ClassHKTypeClassicLength444 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000180495#SPN7465_RS01325Stable P2CS identifier used across views.
GenomeGCF_000180495Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length444 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 444 aa (39.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa444 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
326-434 aa · 109 aa · 24.5% of protein
Raw token
HATPase_c:326:2.72e-29:434:109:109- Raw architecture: HisKA:216:0.000000000045:283:68:64#HATPase_c:326:2.72e-29:434:109:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000180495::NZ_CACF01000001.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span250356-252354Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000180495::NZ_CACF01000001.1::G00013Context members
SPN7465_RS01320SPN7465_RS01325
Partner locus tags
SPN7465_RS01320SPN7465_RS01325
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000491790.1Primary protein accession used for annex mappings.
UniProt accessionC1C6E3Primary UniProt accession resolved in the annex database.
UniProt IDC1C6E3_STRP7Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSPN7465_RS01325Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CACF01000001.1Sequence record reported by the local genomic context database.
Genomic interval251 020-252 354 nt1 335 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span250 356-252 354 ntGCF_000180495::NZ_CACF01000001.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000180495::NZ_CACF01000001.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CACF01000001.1All displayed genes belong to this local TCS context.
Neighborhood span250 356-252 354 nt1 999 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
250 356 nt252 354 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SPN7465_RS01320GCF_000180495#SPN7465_RS01320
RROmpR
250 356-251 030 nt · Forward (+)
SPN7465_RS01325GCF_000180495#SPN7465_RS01325
HKClassicCurrent focus
251 020-252 354 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_019399005#I5899_RS01965Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1943391
Simplified PFAM architecture for HKOC_1943391
PFAM domain coverage: 176 / 452 aa (38.9%)
1 aa452 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[217-283] | HATPase_c[327-435]
- Domain count: 2
- Matched identifier: HKOC_1943391
- Positioned domains: HisKA 217-283 ; HATPase_c 327-435
Cluster members and taxonomy
Representative gene: GCF_019399005#I5899_RS01965
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 869 313 · GCF_000180495
AssemblyASM18049v1 · Contighaploid
Genome composition2 084 938 bp · 39,5% GCStreptococcus pneumoniae SPN7465
Signal transduction countsGenes 27 · HK 13 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key