Gene detail

HMPREF9350_RS02455

Histidine kinase, Classic

Escherichia coli MS 85-1 · GCF_000179075

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000179075#HMPREF9350_RS02455Stable P2CS identifier used across views.
GenomeGCF_000179075Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1858451Run 6 · 55 sequences · id 100% · cov 80%
External referencesWP_001211919.1 · A0AAN3M4Z2 · MIST4 HMPREF9350_RS02455RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
HisKA: 237-299 aa (63 aa)1HATPase_c: 345-451 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw tokenHisKA:237:0.00000000000111:299:63:64
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw tokenHATPase_c:345:2e-34:451:110:109
  • Raw architecture: HisKA:237:0.00000000000111:299:63:64#HATPase_c:345:2e-34:451:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000179075::NZ_ADWQ01000061.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3753-6451Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9350_05474RefSeq proteinWP_001211919.1
Context group IDGCF_000179075::NZ_ADWQ01000061.1::G00002
Context members
HMPREF9350_RS02460HMPREF9350_RS02455
Partner locus tags
HMPREF9350_RS02460HMPREF9350_RS02455
Partner old locus tags
HMPREF9350_05473HMPREF9350_05474
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001211919.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN3M4Z2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN3M4Z2_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9350_RS02455Primary locus identifier stored in the genes table.
Old locus tagHMPREF9350_05474Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ADWQ01000061.1Sequence record reported by the local genomic context database.
Genomic interval5 075-6 451 nt1 377 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 753-6 451 ntGCF_000179075::NZ_ADWQ01000061.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000179075::NZ_ADWQ01000061.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADWQ01000061.1All displayed genes belong to this local TCS context.
Neighborhood span3 753-6 451 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 753 nt6 451 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9350_RS02460GCF_000179075#HMPREF9350_RS02460
RRNtrC

3 753-5 078 nt · Reverse (-)

Old locus HMPREF9350_05473RefSeq WP_000148507.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858451Run 6 · HK · 55 sequences
Representative sequenceGCF_000164215#HMPREF9536_RS01390Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858451

Simplified PFAM architecture for HKOC_1858451

PFAM domain coverage: 168 / 458 aa (36.7%)

1 aa458 aa
HisKA: 238-300 aaHisKAHATPase_c: 346-450 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[238-300] | HATPase_c[346-450]
  • Domain count: 2
  • Matched identifier: HKOC_1858451
  • Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164215#HMPREF9536_RS01390

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 679 202 · GCF_000179075
AssemblyASM17907v1 · Contighaploid
Genome composition5 457 657 bp · 50,5% GCEscherichia coli MS 85-1
Signal transduction countsGenes 63 · HK 30 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key