Gene detail

EC536_RS0118050

Histidine kinase, Classic

Escherichia coli O157:H7 str. EC536 · GCF_000178795

ClassHKTypeClassicLength513 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000178795#EC536_RS0118050Stable P2CS identifier used across views.
GenomeGCF_000178795Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1414830Run 6 · 1429 sequences · id 100% · cov 80%
External referencesWP_000089287.1 · A0AAV3HG03 · MIST4 EC536_RS0118050RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

MASE1HisKA_3HATPase_c
Protein length513 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage418 / 513 aa (81.5%)Merged over positioned domains only.
Domain description1 MASE1,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa513 aa
MASE1: 11-281 aa (271 aa)1HisKA_3: 316-380 aa (65 aa)2HATPase_c: 424-505 aa (82 aa)3
Domain-by-domain annotation3 items
1 MASE1#1
11-281 aa · 271 aa · 52.8% of protein
Raw tokenMASE1:11:2.69e-50:281:299:299
2 HisKA_3#2
316-380 aa · 65 aa · 12.7% of protein
Raw tokenHisKA_3:316:1.38e-16:380:67:68
3 HATPase_c#3
424-505 aa · 82 aa · 16.0% of protein
Raw tokenHATPase_c:424:2.07e-17:505:101:109
  • Raw architecture: MASE1:11:2.69e-50:281:299:299#HisKA_3:316:1.38e-16:380:67:68#HATPase_c:424:2.07e-17:505:101:109
  • Domain description: 1 MASE1,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000178795::NZ_ADVC01000521.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span121352-123522Genomic interval covered by the local TCS group.
Context group IDGCF_000178795::NZ_ADVC01000521.1::G00013
Context members
EC536_RS0118045EC536_RS0118050
Partner locus tags
EC536_RS0118045EC536_RS0118050
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000089287.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3HG03Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3HG03_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEC536_RS0118050Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_ADVC01000521.1Sequence record reported by the local genomic context database.
Genomic interval121 981-123 522 nt1 542 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span121 352-123 522 ntGCF_000178795::NZ_ADVC01000521.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000178795::NZ_ADVC01000521.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADVC01000521.1All displayed genes belong to this local TCS context.
Neighborhood span121 352-123 522 nt2 171 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
121 352 nt123 522 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EC536_RS0118045GCF_000178795#EC536_RS0118045
RRunclassified

121 352-121 981 nt · Forward (+)

RefSeq WP_000621918.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1414830Run 6 · HK · 1429 sequences
Representative sequenceGCF_000006665#Z_RS02120Use this link to inspect the representative gene detail.
PFAM architectureMASE1 + HisKA_3 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1414830

Simplified PFAM architecture for HKOC_1414830

PFAM domain coverage: 419 / 513 aa (81.7%)

1 aa513 aa
MASE1: 11-281 aaMASE1HisKA_3: 316-380 aaHisKA_3HATPase_c: 423-505 aaHATPase_c
MASE1HisKA_3HATPase_c
  • Simplified architecture: MASE1 + HisKA_3 + HATPase_c
  • Raw architecture: MASE1[11-281] | HisKA_3[316-380] | HATPase_c[423-505]
  • Domain count: 3
  • Matched identifier: HKOC_1414830
  • Positioned domains: MASE1 11-281 ; HisKA_3 316-380 ; HATPase_c 423-505
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006665#Z_RS02120

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 702 436 · GCF_000178795
AssemblyASM17879v1 · Contighaploid
Genome composition5 262 452 bp · 50,0% GCEscherichia coli O157:H7 str. EC536
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key