1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw token
HAMP:72:0.00000092:139:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EC536_RS0105760
Histidine kinase, Classic
Escherichia coli O157:H7 str. EC536 · GCF_000178795
ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000178795#EC536_RS0105760Stable P2CS identifier used across views.
GenomeGCF_000178795Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
Domain-by-domain annotation3 items
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw token
HisKA:147:0.00000000186:204:61:643 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw token
HATPase_c:252:7.61e-22:360:111:109- Raw architecture: HAMP:72:0.00000092:139:68:69#HisKA:147:0.00000000186:204:61:64#HATPase_c:252:7.61e-22:360:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000178795::NZ_ADVC01000186.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span93408-95177Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000178795::NZ_ADVC01000186.1::G00030Context members
EC536_RS0105755EC536_RS0105760
Partner locus tags
EC536_RS0105755EC536_RS0105760
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001052137.1Primary protein accession used for annex mappings.
UniProt accessionQ8XDU5Primary UniProt accession resolved in the annex database.
UniProt IDQ8XDU5_ECO57Display identifier provided by UniProt.
GO / PubMed3 / 2Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEC536_RS0105760Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_ADVC01000186.1Sequence record reported by the local genomic context database.
Genomic interval94 077-95 177 nt1 101 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span93 408-95 177 ntGCF_000178795::NZ_ADVC01000186.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000178795::NZ_ADVC01000186.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADVC01000186.1All displayed genes belong to this local TCS context.
Neighborhood span93 408-95 177 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
93 408 nt95 177 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EC536_RS0105755GCF_000178795#EC536_RS0105755
RROmpR
93 408-94 076 nt · Forward (+)
EC536_RS0105760GCF_000178795#EC536_RS0105760
HKClassicCurrent focus
94 077-95 177 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006665#Z_RS26735Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2711907
Simplified PFAM architecture for HKOC_2711907
PFAM domain coverage: 165 / 366 aa (45.1%)
1 aa366 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[147-203] | HATPase_c[252-359]
- Domain count: 2
- Matched identifier: HKOC_2711907
- Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Representative gene: GCF_000006665#Z_RS26735
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 702 436 · GCF_000178795
AssemblyASM17879v1 · Contighaploid
Genome composition5 262 452 bp · 50,0% GCEscherichia coli O157:H7 str. EC536
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key