Gene detail

MBRIFRIK2000_RS0100170

Histidine kinase, Classic

Escherichia coli O157:H7 str. FRIK2000 · GCF_000175755

ClassHKTypeClassicLength475 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000175755#MBRIFRIK2000_RS0100170Stable P2CS identifier used across views.
GenomeGCF_000175755Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1664337Run 6 · 1731 sequences · id 100% · cov 80%
External referencesWP_001301750.1 · A0AAV3H5X2 · MIST4 MBRIFRIK2000_RS0100170RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 475 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
HAMP: 175-243 aa (69 aa)1HisKA: 249-316 aa (68 aa)2HATPase_c: 362-469 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
175-243 aa · 69 aa · 14.5% of protein
Raw tokenHAMP:175:0.000000402:243:69:69
2 HisKA#2
249-316 aa · 68 aa · 14.3% of protein
Raw tokenHisKA:249:0.0000000000000146:316:68:64
3 HATPase_c#3
362-469 aa · 108 aa · 22.7% of protein
Raw tokenHATPase_c:362:1.52e-23:469:108:109
  • Raw architecture: HAMP:175:0.000000402:243:69:69#HisKA:249:0.0000000000000146:316:68:64#HATPase_c:362:1.52e-23:469:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000175755::NZ_ACXO01000001.1::G00039
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span34778-36205Genomic interval covered by the local TCS group.
Context group IDGCF_000175755::NZ_ACXO01000001.1::G00039
Context members
MBRIFRIK2000_RS0100170
Partner locus tags
MBRIFRIK2000_RS0100170
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001301750.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3H5X2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3H5X2_ECOLXDisplay identifier provided by UniProt.
GO / PubMed6 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagMBRIFRIK2000_RS0100170Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_ACXO01000001.1Sequence record reported by the local genomic context database.
Genomic interval34 778-36 205 nt1 428 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span34 778-36 205 ntGCF_000175755::NZ_ACXO01000001.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000175755::NZ_ACXO01000001.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ACXO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span34 778-36 205 nt1 428 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
34 778 nt36 205 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1664337Run 6 · HK · 1731 sequences
Representative sequenceGCF_000006665#Z_RS18020Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1664337

Simplified PFAM architecture for HKOC_1664337

PFAM domain coverage: 229 / 475 aa (48.2%)

1 aa475 aa
HAMP: 192-244 aaHAMPHisKA: 250-316 aaHisKAHATPase_c: 362-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[192-244] | HisKA[250-316] | HATPase_c[362-470]
  • Domain count: 3
  • Matched identifier: HKOC_1664337
  • Positioned domains: HAMP 192-244 ; HisKA 250-316 ; HATPase_c 362-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006665#Z_RS18020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 637 388 · GCF_000175755
AssemblyASM17575v1 · Contighaploid
Genome composition5 408 690 bp · 50,0% GCEscherichia coli O157:H7 str. FRIK2000
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key