1 HAMP#1
293-360 aa · 68 aa · 9.0% of protein
Raw token
HAMP:293:0.0000000000405:360:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECH7EC508_RS05295
Histidine kinase, Hybrid
Escherichia coli O157:H7 str. EC508 · GCF_000172055
ClassHKTypeHybridLength756 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000172055#ECH7EC508_RS05295Stable P2CS identifier used across views.
GenomeGCF_000172055Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_cResponse_reg
Protein length756 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage357 / 756 aa (47.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa756 aa
Domain-by-domain annotation4 items
2 HisKA#2
400-461 aa · 62 aa · 8.2% of protein
Raw token
HisKA:400:0.000000421:461:63:643 HATPase_c#3
504-620 aa · 117 aa · 15.5% of protein
Raw token
HATPase_c:504:2.39e-24:620:118:1094 Response_reg#4
643-752 aa · 110 aa · 14.6% of protein
Raw token
Response_reg:643:0.00000000000154:752:119:111- Raw architecture: HAMP:293:0.0000000000405:360:68:69#HisKA:400:0.000000421:461:63:64#HATPase_c:504:2.39e-24:620:118:109#Response_reg:643:0.00000000000154:752:119:111
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000172055::NZ_ABHW01000005.1::G00031
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span46281-48551Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECH7EC508_3223RefSeq proteinWP_001303083.1
Context group ID
GCF_000172055::NZ_ABHW01000005.1::G00031Context members
ECH7EC508_RS05295
Partner locus tags
ECH7EC508_RS05295
Partner old locus tags
ECH7EC508_3223
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_001303083.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECH7EC508_RS05295Primary locus identifier stored in the genes table.
Old locus tagECH7EC508_3223Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ABHW01000005.1Sequence record reported by the local genomic context database.
Genomic interval46 281-48 551 nt2 271 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span46 281-48 551 ntGCF_000172055::NZ_ABHW01000005.1::G00031
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000172055::NZ_ABHW01000005.1::G00031Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ABHW01000005.1All displayed genes belong to this local TCS context.
Neighborhood span46 281-48 551 nt2 271 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
46 281 nt48 551 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ECH7EC508_RS05295GCF_000172055#ECH7EC508_RS05295
HKHybridCurrent focus
46 281-48 551 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000172055#ECH7EC508_RS05295The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0653535
Simplified PFAM architecture for HKOC_0653535
PFAM domain coverage: 335 / 756 aa (44.3%)
1 aa756 aa
HAMPHisKAHATPase_cResponse_reg
- Simplified architecture: HAMP + HisKA + HATPase_c + Response_reg
- Raw architecture: HAMP[312-360] | HisKA[402-461] | HATPase_c[504-619] | Response_reg[643-752]
- Domain count: 4
- Matched identifier: HKOC_0653535
- Positioned domains: HAMP 312-360 ; HisKA 402-461 ; HATPase_c 504-619 ; Response_reg 643-752
Cluster members and taxonomy
Representative gene: GCF_000172055#ECH7EC508_RS05295
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 478 007 · GCF_000172055
AssemblyASM17205v1 · Contighaploid
Genome composition5 656 666 bp · 50,5% GCEscherichia coli O157:H7 str. EC508
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key