Gene detail

ECH7EC4486_RS04670

Histidine kinase, Classic

Escherichia coli O157:H7 str. EC4486 · GCF_000171995

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000171995#ECH7EC4486_RS04670Stable P2CS identifier used across views.
GenomeGCF_000171995Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1674236Run 6 · 8 sequences · id 100% · cov 80%
External referencesWP_001219592.1 · MIST4 ECH7EC4486_RS04670RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 474 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 184-251 aa (68 aa)1HisKA: 257-319 aa (63 aa)2HATPase_c: 365-469 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
184-251 aa · 68 aa · 14.3% of protein
Raw tokenHAMP:184:0.000000000553:251:68:69
2 HisKA#2
257-319 aa · 63 aa · 13.3% of protein
Raw tokenHisKA:257:0.000000000000602:319:63:64
3 HATPase_c#3
365-469 aa · 105 aa · 22.2% of protein
Raw tokenHATPase_c:365:7.33e-24:469:105:109
  • Raw architecture: HAMP:184:0.000000000553:251:68:69#HisKA:257:0.000000000000602:319:63:64#HATPase_c:365:7.33e-24:469:105:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000171995::NZ_ABHS01000002.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span442159-444272Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECH7EC4486_2126RefSeq proteinWP_001219592.1
Context group IDGCF_000171995::NZ_ABHS01000002.1::G00035
Context members
ECH7EC4486_RS04665ECH7EC4486_RS04670
Partner locus tags
ECH7EC4486_RS04665ECH7EC4486_RS04670
Partner old locus tags
ECH7EC4486_2125ECH7EC4486_2126
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_001219592.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECH7EC4486_RS04670Primary locus identifier stored in the genes table.
Old locus tagECH7EC4486_2126Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ABHS01000002.1Sequence record reported by the local genomic context database.
Genomic interval442 848-444 272 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span442 159-444 272 ntGCF_000171995::NZ_ABHS01000002.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000171995::NZ_ABHS01000002.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ABHS01000002.1All displayed genes belong to this local TCS context.
Neighborhood span442 159-444 272 nt2 114 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
442 159 nt444 272 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECH7EC4486_RS04665GCF_000171995#ECH7EC4486_RS04665
RROmpR

442 159-442 848 nt · Forward (+)

Old locus ECH7EC4486_2125RefSeq WP_001188676.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674236Run 6 · HK · 8 sequences
Representative sequenceGCF_000171975#ECH7EC4401_RS17775Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674236

Simplified PFAM architecture for HKOC_1674236

PFAM domain coverage: 217 / 474 aa (45.8%)

1 aa474 aa
HAMP: 202-251 aaHAMPHisKA: 258-319 aaHisKAHATPase_c: 365-469 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[202-251] | HisKA[258-319] | HATPase_c[365-469]
  • Domain count: 3
  • Matched identifier: HKOC_1674236
  • Positioned domains: HAMP 202-251 ; HisKA 258-319 ; HATPase_c 365-469
Cluster members and taxonomy
Visualization

Representative gene: GCF_000171975#ECH7EC4401_RS17775

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 478 005 · GCF_000171995
AssemblyASM17199v1 · Contighaploid
Genome composition5 933 166 bp · 50,5% GCEscherichia coli O157:H7 str. EC4486
Signal transduction countsGenes 61 · HK 30 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key