Gene detail

RUMGNA_RS04660

Histidine kinase, Classic

Mediterraneibacter gnavus ATCC 29149 · GCF_000169475

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000169475#RUMGNA_RS04660Stable P2CS identifier used across views.
GenomeGCF_000169475Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1047501Run 6 · 70 sequences · id 100% · cov 80% · representative
External referencesWP_023924249.1 · A0A829NH68 · MIST4 RUMGNA_RS04660RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage505 / 601 aa (84.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 44-287 aa (244 aa)1HAMP: 306-375 aa (70 aa)2His_kinase: 390-469 aa (80 aa)3HATPase_c: 481-591 aa (111 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
44-287 aa · 244 aa · 40.6% of protein
Raw tokendCache_1:44:1.75e-19:287:248:195
2 HAMP#2
306-375 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:306:0.00000000000104:375:70:69
3 His_kinase#3
390-469 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:390:2.78e-36:469:80:80
4 HATPase_c#4
481-591 aa · 111 aa · 18.5% of protein
Raw tokenHATPase_c:481:6.74e-16:591:115:109
  • Raw architecture: dCache_1:44:1.75e-19:287:248:195#HAMP:306:0.00000000000104:375:70:69#His_kinase:390:2.78e-36:469:80:80#HATPase_c:481:6.74e-16:591:115:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000169475::NZ_AAYG02000009.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span134789-138202Genomic interval covered by the local TCS group.
Identifiers
Old locus tagRUMGNA_01061RefSeq proteinWP_023924249.1
Context group IDGCF_000169475::NZ_AAYG02000009.1::G00041
Context members
RUMGNA_RS04655RUMGNA_RS04660
Partner locus tags
RUMGNA_RS04655RUMGNA_RS04660
Partner old locus tags
RUMGNA_01060RUMGNA_01061
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_023924249.1Primary protein accession used for annex mappings.
UniProt accessionA0A829NH68Primary UniProt accession resolved in the annex database.
UniProt IDA0A829NH68_MEDG5Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagRUMGNA_RS04660Primary locus identifier stored in the genes table.
Old locus tagRUMGNA_01061Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AAYG02000009.1Sequence record reported by the local genomic context database.
Genomic interval136 397-138 202 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span134 789-138 202 ntGCF_000169475::NZ_AAYG02000009.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000169475::NZ_AAYG02000009.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AAYG02000009.1All displayed genes belong to this local TCS context.
Neighborhood span134 789-138 202 nt3 414 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
134 789 nt138 202 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

RUMGNA_RS04655GCF_000169475#RUMGNA_RS04655
RRunclassified

134 789-136 393 nt · Forward (+)

Old locus RUMGNA_01060RefSeq WP_009244981.1
RUMGNA_RS04660GCF_000169475#RUMGNA_RS04660
HKClassicCurrent focus

136 397-138 202 nt · Forward (+)

Old locus RUMGNA_01061RefSeq WP_023924249.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1047501Run 6 · HK · 70 sequences
Representative sequenceGCF_000169475#RUMGNA_RS04660The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1047501

Simplified PFAM architecture for HKOC_1047501

PFAM domain coverage: 484 / 601 aa (80.5%)

1 aa601 aa
dCache_1: 45-287 aadCache_1HAMP: 322-374 aaHAMPHis_kinase: 390-469 aaHis_kinaseHATPase_c: 484-591 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[45-287] | HAMP[322-374] | His_kinase[390-469] | HATPase_c[484-591]
  • Domain count: 4
  • Matched identifier: HKOC_1047501
  • Positioned domains: dCache_1 45-287 ; HAMP 322-374 ; His_kinase 390-469 ; HATPase_c 484-591
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS04660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 411 470 · GCF_000169475
AssemblyASM16947v1 · Contighaploid
Genome composition3 501 911 bp · 43,0% GCMediterraneibacter gnavus ATCC 29149
Signal transduction countsGenes 81 · HK 39 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key