Gene detail

HMPREF0219_RS04695

Histidine kinase, Classic

Clostridioides difficile NAP07 · GCF_000164655

ClassHKTypeClassicLength448 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164655#HMPREF0219_RS04695Stable P2CS identifier used across views.
GenomeGCF_000164655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1772968Run 6 · 304 sequences · id 100% · cov 80%
External referencesWP_223844870.1 · MIST4 HMPREF0219_RS04695RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length448 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 448 aa (38.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa448 aa
HisKA: 228-296 aa (69 aa)1HATPase_c: 343-447 aa (105 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
228-296 aa · 69 aa · 15.4% of protein
Raw tokenHisKA:228:0.000000000000416:296:69:64
2 HATPase_c#2
343-447 aa · 105 aa · 23.4% of protein
Raw tokenHATPase_c:343:1.97e-28:447:106:109
  • Raw architecture: HisKA:228:0.000000000000416:296:69:64#HATPase_c:343:1.97e-28:447:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000164655::NZ_GG770749.1::G00017
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span409558-410904Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0219_1723RefSeq proteinWP_223844870.1
Context group IDGCF_000164655::NZ_GG770749.1::G00017
Context members
HMPREF0219_RS04695
Partner locus tags
HMPREF0219_RS04695
Partner old locus tags
HMPREF0219_1723
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_223844870.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0219_RS04695Primary locus identifier stored in the genes table.
Old locus tagHMPREF0219_1723Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770749.1Sequence record reported by the local genomic context database.
Genomic interval409 558-410 904 nt1 347 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span409 558-410 904 ntGCF_000164655::NZ_GG770749.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164655::NZ_GG770749.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770749.1All displayed genes belong to this local TCS context.
Neighborhood span409 558-410 904 nt1 347 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
409 558 nt410 904 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1772968Run 6 · HK · 304 sequences
Representative sequenceGCF_000155065#QAE_RS0209365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1772968

Simplified PFAM architecture for HKOC_1772968

PFAM domain coverage: 167 / 465 aa (35.9%)

1 aa465 aa
HisKA: 245-306 aaHisKAHATPase_c: 360-464 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-306] | HATPase_c[360-464]
  • Domain count: 2
  • Matched identifier: HKOC_1772968
  • Positioned domains: HisKA 245-306 ; HATPase_c 360-464
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0209365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 258 · GCF_000164655
AssemblyASM16465v1 · Scaffoldhaploid
Genome composition3 905 466 bp · 28,5% GCClostridioides difficile NAP07
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key