Gene detail

HMPREF0219_RS04660

Histidine kinase, Classic

Clostridioides difficile NAP07 · GCF_000164655

ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164655#HMPREF0219_RS04660Stable P2CS identifier used across views.
GenomeGCF_000164655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2884672Run 6 · 303 sequences · id 100% · cov 80%
External referencesWP_003424113.1 · D5Q437 · MIST4 HMPREF0219_RS04660RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 302 aa (55.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
HisKA: 82-144 aa (63 aa)1HATPase_c: 192-295 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw tokenHisKA:82:0.0000000759:144:63:64
2 HATPase_c#2
192-295 aa · 104 aa · 34.4% of protein
Raw tokenHATPase_c:192:8.03e-23:295:104:109
  • Raw architecture: HisKA:82:0.0000000759:144:63:64#HATPase_c:192:8.03e-23:295:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164655::NZ_GG770749.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span419025-420606Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0219_1730RefSeq proteinWP_003424113.1
Context group IDGCF_000164655::NZ_GG770749.1::G00018
Context members
HMPREF0219_RS04660HMPREF0219_RS04655
Partner locus tags
HMPREF0219_RS04660HMPREF0219_RS04655
Partner old locus tags
HMPREF0219_1730HMPREF0219_1731
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003424113.1Primary protein accession used for annex mappings.
UniProt accessionD5Q437Primary UniProt accession resolved in the annex database.
UniProt IDD5Q437_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0219_RS04660Primary locus identifier stored in the genes table.
Old locus tagHMPREF0219_1730Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770749.1Sequence record reported by the local genomic context database.
Genomic interval419 025-419 933 nt909 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span419 025-420 606 ntGCF_000164655::NZ_GG770749.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164655::NZ_GG770749.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770749.1All displayed genes belong to this local TCS context.
Neighborhood span419 025-420 606 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
419 025 nt420 606 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0219_RS04655GCF_000164655#HMPREF0219_RS04655
RROmpR

419 935-420 606 nt · Reverse (-)

Old locus HMPREF0219_1731RefSeq WP_003424114.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2884672Run 6 · HK · 303 sequences
Representative sequenceGCF_000155065#QAE_RS0209400Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2884672

Simplified PFAM architecture for HKOC_2884672

PFAM domain coverage: 168 / 302 aa (55.6%)

1 aa302 aa
HisKA: 82-144 aaHisKAHATPase_c: 192-296 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[82-144] | HATPase_c[192-296]
  • Domain count: 2
  • Matched identifier: HKOC_2884672
  • Positioned domains: HisKA 82-144 ; HATPase_c 192-296
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0209400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 258 · GCF_000164655
AssemblyASM16465v1 · Scaffoldhaploid
Genome composition3 905 466 bp · 28,5% GCClostridioides difficile NAP07
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key