1 PAS#1
11-99 aa · 89 aa · 25.5% of protein
Raw token
PAS:11:0.000000682:99:92:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9549_RS19370
Histidine kinase, Classic
Escherichia coli MS 185-1 · GCF_000164575
ClassHKTypeClassicLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164575#HMPREF9549_RS19370Stable P2CS identifier used across views.
GenomeGCF_000164575Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 349 aa (74.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Domain-by-domain annotation3 items
2 HisKA#2
131-186 aa · 56 aa · 16.0% of protein
Raw token
HisKA:131:0.00000000000067:186:56:643 HATPase_c#3
234-349 aa · 116 aa · 33.2% of protein
Raw token
HATPase_c:234:4.49e-24:349:120:109- Raw architecture: PAS:11:0.000000682:99:92:113#HisKA:131:0.00000000000067:186:56:64#HATPase_c:234:4.49e-24:349:120:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164575::NZ_GG774220.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9962-12432Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9549_00774RefSeq proteinWP_000190574.1
Context group ID
GCF_000164575::NZ_GG774220.1::G00037Context members
HMPREF9549_RS19375HMPREF9549_RS19370
Partner locus tags
HMPREF9549_RS19375HMPREF9549_RS19370
Partner old locus tags
HMPREF9549_00773HMPREF9549_00774
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000190574.1Primary protein accession used for annex mappings.
UniProt accessionB7N2L1Primary UniProt accession resolved in the annex database.
UniProt IDB7N2L1_ECO81Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9549_RS19370Primary locus identifier stored in the genes table.
Old locus tagHMPREF9549_00774Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774220.1Sequence record reported by the local genomic context database.
Genomic interval11 383-12 432 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 962-12 432 ntGCF_000164575::NZ_GG774220.1::G00037
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164575::NZ_GG774220.1::G00037Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774220.1All displayed genes belong to this local TCS context.
Neighborhood span9 962-12 432 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 962 nt12 432 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9549_RS19375GCF_000164575#HMPREF9549_RS19375
RRNtrC
9 962-11 371 nt · Reverse (-)
HMPREF9549_RS19370GCF_000164575#HMPREF9549_RS19370
HKClassicCurrent focus
11 383-12 432 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS22760Use this link to inspect the representative gene detail.
PFAM architecturePAS + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2800896
Simplified PFAM architecture for HKOC_2800896
PFAM domain coverage: 260 / 349 aa (74.5%)
1 aa349 aa
PASHisKAHATPase_c
- Simplified architecture: PAS + HisKA + HATPase_c
- Raw architecture: PAS[11-99] | HisKA[131-186] | HATPase_c[234-348]
- Domain count: 3
- Matched identifier: HKOC_2800896
- Positioned domains: PAS 11-99 ; HisKA 131-186 ; HATPase_c 234-348
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS22760
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 546 · GCF_000164575
AssemblyASM16457v1 · Scaffoldhaploid
Genome composition4 962 359 bp · 50,5% GCEscherichia coli MS 185-1
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key