1 PilJ#1
35-128 aa · 94 aa · 15.7% of protein
Raw token
PilJ:35:0.0000000066:128:112:112P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9549_RS18580
Histidine kinase, Classic
Escherichia coli MS 185-1 · GCF_000164575
ClassHKTypeClassicLength598 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164575#HMPREF9549_RS18580Stable P2CS identifier used across views.
GenomeGCF_000164575Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PilJHAMPHisKA_3HATPase_c
Protein length598 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage314 / 598 aa (52.5%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa598 aa
Domain-by-domain annotation4 items
2 HAMP#2
158-225 aa · 68 aa · 11.4% of protein
Raw token
HAMP:158:0.0000000000604:225:69:693 HisKA_3#3
390-453 aa · 64 aa · 10.7% of protein
Raw token
HisKA_3:390:7.03e-17:453:64:684 HATPase_c#4
496-583 aa · 88 aa · 14.7% of protein
Raw token
HATPase_c:496:6.01e-20:583:103:109- Raw architecture: PilJ:35:0.0000000066:128:112:112#HAMP:158:0.0000000000604:225:69:69#HisKA_3:390:7.03e-17:453:64:68#HATPase_c:496:6.01e-20:583:103:109
- Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164575::NZ_GG774221.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span61993-64432Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9549_00965RefSeq proteinWP_000918039.1
Context group ID
GCF_000164575::NZ_GG774221.1::G00035Context members
HMPREF9549_RS18585HMPREF9549_RS18580
Partner locus tags
HMPREF9549_RS18585HMPREF9549_RS18580
Partner old locus tags
HMPREF9549_00964HMPREF9549_00965
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000918039.1Primary protein accession used for annex mappings.
UniProt accessionA0A234MT01Primary UniProt accession resolved in the annex database.
UniProt IDA0A234MT01_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9549_RS18580Primary locus identifier stored in the genes table.
Old locus tagHMPREF9549_00965Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774221.1Sequence record reported by the local genomic context database.
Genomic interval62 636-64 432 nt1 797 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span61 993-64 432 ntGCF_000164575::NZ_GG774221.1::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164575::NZ_GG774221.1::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774221.1All displayed genes belong to this local TCS context.
Neighborhood span61 993-64 432 nt2 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
61 993 nt64 432 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9549_RS18585GCF_000164575#HMPREF9549_RS18585
RRNarL
61 993-62 643 nt · Reverse (-)
HMPREF9549_RS18580GCF_000164575#HMPREF9549_RS18580
HKClassicCurrent focus
62 636-64 432 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS07855Use this link to inspect the representative gene detail.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1061533
Simplified PFAM architecture for HKOC_1061533
PFAM domain coverage: 301 / 598 aa (50.3%)
1 aa598 aa
PilJHAMPHisKA_3HATPase_c
- Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
- Raw architecture: PilJ[35-129] | HAMP[173-224] | HisKA_3[390-453] | HATPase_c[496-585]
- Domain count: 4
- Matched identifier: HKOC_1061533
- Positioned domains: PilJ 35-129 ; HAMP 173-224 ; HisKA_3 390-453 ; HATPase_c 496-585
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS07855
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 546 · GCF_000164575
AssemblyASM16457v1 · Scaffoldhaploid
Genome composition4 962 359 bp · 50,5% GCEscherichia coli MS 185-1
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key