1 HAMP#1
184-251 aa · 68 aa · 14.3% of protein
Raw token
HAMP:184:0.00000000022:251:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9549_RS12235
Histidine kinase, Classic
Escherichia coli MS 185-1 · GCF_000164575
ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164575#HMPREF9549_RS12235Stable P2CS identifier used across views.
GenomeGCF_000164575Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 474 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
Domain-by-domain annotation3 items
2 HisKA#2
257-319 aa · 63 aa · 13.3% of protein
Raw token
HisKA:257:0.000000000000419:319:63:643 HATPase_c#3
365-469 aa · 105 aa · 22.2% of protein
Raw token
HATPase_c:365:1.72e-23:469:105:109- Raw architecture: HAMP:184:0.00000000022:251:68:69#HisKA:257:0.000000000000419:319:63:64#HATPase_c:365:1.72e-23:469:105:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164575::NZ_GG774242.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span117954-120067Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9549_02407RefSeq proteinWP_001219587.1
Context group ID
GCF_000164575::NZ_GG774242.1::G00023Context members
HMPREF9549_RS12240HMPREF9549_RS12235
Partner locus tags
HMPREF9549_RS12240HMPREF9549_RS12235
Partner old locus tags
HMPREF9549_02406HMPREF9549_02407
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_001219587.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9549_RS12235Primary locus identifier stored in the genes table.
Old locus tagHMPREF9549_02407Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774242.1Sequence record reported by the local genomic context database.
Genomic interval118 643-120 067 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span117 954-120 067 ntGCF_000164575::NZ_GG774242.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164575::NZ_GG774242.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774242.1All displayed genes belong to this local TCS context.
Neighborhood span117 954-120 067 nt2 114 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
117 954 nt120 067 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9549_RS12240GCF_000164575#HMPREF9549_RS12240
RROmpR
117 954-118 643 nt · Forward (+)
HMPREF9549_RS12235GCF_000164575#HMPREF9549_RS12235
HKClassicCurrent focus
118 643-120 067 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164575#HMPREF9549_RS12235The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1674217
Simplified PFAM architecture for HKOC_1674217
PFAM domain coverage: 217 / 474 aa (45.8%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[202-251] | HisKA[258-319] | HATPase_c[365-469]
- Domain count: 3
- Matched identifier: HKOC_1674217
- Positioned domains: HAMP 202-251 ; HisKA 258-319 ; HATPase_c 365-469
Cluster members and taxonomy
Representative gene: GCF_000164575#HMPREF9549_RS12235
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 546 · GCF_000164575
AssemblyASM16457v1 · Scaffoldhaploid
Genome composition4 962 359 bp · 50,5% GCEscherichia coli MS 185-1
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key