1 HAMP#1
188-257 aa · 70 aa · 14.6% of protein
Raw token
HAMP:188:0.00000000006:257:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9549_RS06590
Histidine kinase, Classic
Escherichia coli MS 185-1 · GCF_000164575
ClassHKTypeClassicLength480 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164575#HMPREF9549_RS06590Stable P2CS identifier used across views.
GenomeGCF_000164575Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length480 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 480 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa480 aa
Domain-by-domain annotation3 items
2 HisKA#2
261-327 aa · 67 aa · 14.0% of protein
Raw token
HisKA:261:0.00000000000119:327:67:643 HATPase_c#3
371-479 aa · 109 aa · 22.7% of protein
Raw token
HATPase_c:371:3.87e-29:479:110:109- Raw architecture: HAMP:188:0.00000000006:257:71:69#HisKA:261:0.00000000000119:327:67:64#HATPase_c:371:3.87e-29:479:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164575::NZ_GG774253.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span176329-178444Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9549_03732RefSeq proteinWP_000253819.1
Context group ID
GCF_000164575::NZ_GG774253.1::G00011Context members
HMPREF9549_RS06590HMPREF9549_RS06585
Partner locus tags
HMPREF9549_RS06590HMPREF9549_RS06585
Partner old locus tags
HMPREF9549_03732HMPREF9549_03733
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_000253819.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9549_RS06590Primary locus identifier stored in the genes table.
Old locus tagHMPREF9549_03732Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774253.1Sequence record reported by the local genomic context database.
Genomic interval176 329-177 771 nt1 443 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span176 329-178 444 ntGCF_000164575::NZ_GG774253.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164575::NZ_GG774253.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774253.1All displayed genes belong to this local TCS context.
Neighborhood span176 329-178 444 nt2 116 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
176 329 nt178 444 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9549_RS06590GCF_000164575#HMPREF9549_RS06590
HKClassicCurrent focus
176 329-177 771 nt · Reverse (-)
HMPREF9549_RS06585GCF_000164575#HMPREF9549_RS06585
RROmpR
177 761-178 444 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164575#HMPREF9549_RS06590The current gene is the representative for this cluster.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1619119
Simplified PFAM architecture for HKOC_1619119
PFAM domain coverage: 395 / 480 aa (82.3%)
1 aa480 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-180] | HAMP[210-257] | HisKA[262-326] | HATPase_c[371-479]
- Domain count: 4
- Matched identifier: HKOC_1619119
- Positioned domains: CusS 8-180 ; HAMP 210-257 ; HisKA 262-326 ; HATPase_c 371-479
Cluster members and taxonomy
Representative gene: GCF_000164575#HMPREF9549_RS06590
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 546 · GCF_000164575
AssemblyASM16457v1 · Scaffoldhaploid
Genome composition4 962 359 bp · 50,5% GCEscherichia coli MS 185-1
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key