Gene detail

HMPREF9549_RS05110

Histidine kinase, Classic

Escherichia coli MS 185-1 · GCF_000164575

ClassHKTypeClassicLength433 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164575#HMPREF9549_RS05110Stable P2CS identifier used across views.
GenomeGCF_000164575Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2140159Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_000732515.1 · MIST4 HMPREF9549_RS05110RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length433 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 433 aa (54.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa433 aa
HAMP: 140-207 aa (68 aa)1HisKA: 211-269 aa (59 aa)2HATPase_c: 316-423 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
140-207 aa · 68 aa · 15.7% of protein
Raw tokenHAMP:140:0.0000000403:207:72:69
2 HisKA#2
211-269 aa · 59 aa · 13.6% of protein
Raw tokenHisKA:211:0.000000000316:269:62:64
3 HATPase_c#3
316-423 aa · 108 aa · 24.9% of protein
Raw tokenHATPase_c:316:1.59e-29:423:109:109
  • Raw architecture: HAMP:140:0.0000000403:207:72:69#HisKA:211:0.000000000316:269:62:64#HATPase_c:316:1.59e-29:423:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164575::NZ_GG774265.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24890-26914Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9549_04092RefSeq proteinWP_000732515.1
Context group IDGCF_000164575::NZ_GG774265.1::G00007
Context members
HMPREF9549_RS05110HMPREF9549_RS05105
Partner locus tags
HMPREF9549_RS05110HMPREF9549_RS05105
Partner old locus tags
HMPREF9549_04092HMPREF9549_04093
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_000732515.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9549_RS05110Primary locus identifier stored in the genes table.
Old locus tagHMPREF9549_04092Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774265.1Sequence record reported by the local genomic context database.
Genomic interval24 890-26 191 nt1 302 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span24 890-26 914 ntGCF_000164575::NZ_GG774265.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164575::NZ_GG774265.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774265.1All displayed genes belong to this local TCS context.
Neighborhood span24 890-26 914 nt2 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 890 nt26 914 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9549_RS05105GCF_000164575#HMPREF9549_RS05105
RROmpR

26 195-26 914 nt · Reverse (-)

Old locus HMPREF9549_04093RefSeq WP_001298660.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2140159Run 6 · HK · 1 sequences
Representative sequenceGCF_000164575#HMPREF9549_RS05110The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2140159

Simplified PFAM architecture for HKOC_2140159

PFAM domain coverage: 209 / 433 aa (48.3%)

1 aa433 aa
HAMP: 163-206 aaHAMPHisKA: 212-270 aaHisKAHATPase_c: 318-423 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[163-206] | HisKA[212-270] | HATPase_c[318-423]
  • Domain count: 3
  • Matched identifier: HKOC_2140159
  • Positioned domains: HAMP 163-206 ; HisKA 212-270 ; HATPase_c 318-423
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164575#HMPREF9549_RS05110

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 546 · GCF_000164575
AssemblyASM16457v1 · Scaffoldhaploid
Genome composition4 962 359 bp · 50,5% GCEscherichia coli MS 185-1
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key