1 Hpt#1
7-93 aa · 87 aa · 13.3% of protein
Raw token
Hpt:7:0.00000000000000129:93:87:84P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9549_RS02755
Histidine kinase, CheA
Escherichia coli MS 185-1 · GCF_000164575
ClassHKTypeCheALength654 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164575#HMPREF9549_RS02755Stable P2CS identifier used across views.
GenomeGCF_000164575Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HptH-kinase_dimHATPase_cCheW
Protein length654 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage415 / 654 aa (63.5%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa654 aa
Domain-by-domain annotation4 items
2 H-kinase_dim#2
263-324 aa · 62 aa · 9.5% of protein
Raw token
H-kinase_dim:263:1.61e-18:324:66:673 HATPase_c#3
371-508 aa · 138 aa · 21.1% of protein
Raw token
HATPase_c:371:7.97e-17:508:138:1094 CheW#4
513-640 aa · 128 aa · 19.6% of protein
Raw token
CheW:513:5.27e-30:640:134:138- Raw architecture: Hpt:7:0.00000000000000129:93:87:84#H-kinase_dim:263:1.61e-18:324:66:67#HATPase_c:371:7.97e-17:508:138:109#CheW:513:5.27e-30:640:134:138
- Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000164575::NZ_GG774271.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span98981-100945Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9549_04662RefSeq proteinWP_001441984.1
Context group ID
GCF_000164575::NZ_GG774271.1::G00004Context members
HMPREF9549_RS02755
Partner locus tags
HMPREF9549_RS02755
Partner old locus tags
HMPREF9549_04662
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001441984.1Primary protein accession used for annex mappings.
UniProt accessionA0A2G9ACC8Primary UniProt accession resolved in the annex database.
UniProt IDA0A2G9ACC8_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 2Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9549_RS02755Primary locus identifier stored in the genes table.
Old locus tagHMPREF9549_04662Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774271.1Sequence record reported by the local genomic context database.
Genomic interval98 981-100 945 nt1 965 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span98 981-100 945 ntGCF_000164575::NZ_GG774271.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164575::NZ_GG774271.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774271.1All displayed genes belong to this local TCS context.
Neighborhood span98 981-100 945 nt1 965 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
98 981 nt100 945 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF9549_RS02755GCF_000164575#HMPREF9549_RS02755
HKCheACurrent focus
98 981-100 945 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS10905Use this link to inspect the representative gene detail.
PFAM architectureHpt + CheY-binding + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0886033
Simplified PFAM architecture for HKOC_0886033
PFAM domain coverage: 484 / 654 aa (74.0%)
1 aa654 aa
HptCheY-bindingH-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + CheY-binding + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[8-100] | CheY-binding[161-223] | H-kinase_dim[261-324] | HATPase_c[372-508] | CheW[514-640]
- Domain count: 5
- Matched identifier: HKOC_0886033
- Positioned domains: Hpt 8-100 ; CheY-binding 161-223 ; H-kinase_dim 261-324 ; HATPase_c 372-508 ; CheW 514-640
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS10905
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 546 · GCF_000164575
AssemblyASM16457v1 · Scaffoldhaploid
Genome composition4 962 359 bp · 50,5% GCEscherichia coli MS 185-1
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key