1 HAMP#1
161-229 aa · 69 aa · 15.3% of protein
Raw token
HAMP:161:0.000000000609:229:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9550_RS05100
Histidine kinase, Classic
Escherichia coli MS 187-1 · GCF_000164335
ClassHKTypeClassicLength452 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164335#HMPREF9550_RS05100Stable P2CS identifier used across views.
GenomeGCF_000164335Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length452 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 452 aa (53.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa452 aa
Domain-by-domain annotation3 items
2 HisKA#2
235-299 aa · 65 aa · 14.4% of protein
Raw token
HisKA:235:0.0000000000765:299:65:643 HATPase_c#3
344-452 aa · 109 aa · 24.1% of protein
Raw token
HATPase_c:344:3.77e-17:452:113:109- Raw architecture: HAMP:161:0.000000000609:229:69:69#HisKA:235:0.0000000000765:299:65:64#HATPase_c:344:3.77e-17:452:113:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164335::NZ_GG772563.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25413-27441Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9550_03423RefSeq proteinWP_000826748.1
Context group ID
GCF_000164335::NZ_GG772563.1::G00012Context members
HMPREF9550_RS05100HMPREF9550_RS05095
Partner locus tags
HMPREF9550_RS05100HMPREF9550_RS05095
Partner old locus tags
HMPREF9550_03423HMPREF9550_03424
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000826748.1Primary protein accession used for annex mappings.
UniProt accessionA0A1M1CHX8Primary UniProt accession resolved in the annex database.
UniProt IDA0A1M1CHX8_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9550_RS05100Primary locus identifier stored in the genes table.
Old locus tagHMPREF9550_03423Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772563.1Sequence record reported by the local genomic context database.
Genomic interval25 413-26 771 nt1 359 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span25 413-27 441 ntGCF_000164335::NZ_GG772563.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164335::NZ_GG772563.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772563.1All displayed genes belong to this local TCS context.
Neighborhood span25 413-27 441 nt2 029 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 413 nt27 441 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9550_RS05100GCF_000164335#HMPREF9550_RS05100
HKClassicCurrent focus
25 413-26 771 nt · Reverse (-)
HMPREF9550_RS05095GCF_000164335#HMPREF9550_RS05095
RROmpR
26 680-27 441 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009565#B21_RS09910Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1936937
Simplified PFAM architecture for HKOC_1936937
PFAM domain coverage: 172 / 452 aa (38.1%)
1 aa452 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[236-300] | HATPase_c[345-451]
- Domain count: 2
- Matched identifier: HKOC_1936937
- Positioned domains: HisKA 236-300 ; HATPase_c 345-451
Cluster members and taxonomy
Representative gene: GCF_000009565#B21_RS09910
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 547 · GCF_000164335
AssemblyASM16433v1 · Scaffoldhaploid
Genome composition4 403 159 bp · 51,0% GCEscherichia coli MS 187-1
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key