1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw token
HAMP:165:0.000000000000959:234:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9550_RS03215
Histidine kinase, Classic
Escherichia coli MS 187-1 · GCF_000164335
ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164335#HMPREF9550_RS03215Stable P2CS identifier used across views.
GenomeGCF_000164335Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw token
HisKA:238:7.69e-17:299:63:643 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw token
HATPase_c:345:7.11e-30:453:110:109- Raw architecture: HAMP:165:0.000000000000959:234:70:69#HisKA:238:7.69e-17:299:63:64#HATPase_c:345:7.11e-30:453:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164335::NZ_GG772571.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span130042-132110Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9550_03872RefSeq proteinWP_000580413.1
Context group ID
GCF_000164335::NZ_GG772571.1::G00005Context members
HMPREF9550_RS03220HMPREF9550_RS03215
Partner locus tags
HMPREF9550_RS03220HMPREF9550_RS03215
Partner old locus tags
HMPREF9550_03871HMPREF9550_03872
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000580413.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN4SW22Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN4SW22_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9550_RS03215Primary locus identifier stored in the genes table.
Old locus tagHMPREF9550_03872Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772571.1Sequence record reported by the local genomic context database.
Genomic interval130 737-132 110 nt1 374 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span130 042-132 110 ntGCF_000164335::NZ_GG772571.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164335::NZ_GG772571.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772571.1All displayed genes belong to this local TCS context.
Neighborhood span130 042-132 110 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
130 042 nt132 110 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9550_RS03220GCF_000164335#HMPREF9550_RS03220
RROmpR
130 042-130 740 nt · Forward (+)
HMPREF9550_RS03215GCF_000164335#HMPREF9550_RS03215
HKClassicCurrent focus
130 737-132 110 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009565#B21_RS19905Use this link to inspect the representative gene detail.
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1873345
Simplified PFAM architecture for HKOC_1873345
PFAM domain coverage: 293 / 457 aa (64.1%)
1 aa457 aa
CpxA_periHAMPHisKAHATPase_c
- Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
- Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
- Domain count: 4
- Matched identifier: HKOC_1873345
- Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Representative gene: GCF_000009565#B21_RS19905
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 547 · GCF_000164335
AssemblyASM16433v1 · Scaffoldhaploid
Genome composition4 403 159 bp · 51,0% GCEscherichia coli MS 187-1
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key