1 HAMP#1
164-232 aa · 69 aa · 15.4% of protein
Raw token
HAMP:164:0.0000016:232:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9550_RS02125
Histidine kinase, Classic
Escherichia coli MS 187-1 · GCF_000164335
ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164335#HMPREF9550_RS02125Stable P2CS identifier used across views.
GenomeGCF_000164335Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 449 aa (50.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-301 aa · 64 aa · 14.3% of protein
Raw token
HisKA:238:0.00000000000573:301:64:643 HATPase_c#3
348-442 aa · 95 aa · 21.2% of protein
Raw token
HATPase_c:348:1.18e-25:442:99:109- Raw architecture: HAMP:164:0.0000016:232:70:69#HisKA:238:0.00000000000573:301:64:64#HATPase_c:348:1.18e-25:442:99:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164335::NZ_GG772572.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span191109-193114Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9550_04128RefSeq proteinWP_000673398.1
Context group ID
GCF_000164335::NZ_GG772572.1::G00003Context members
HMPREF9550_RS02130HMPREF9550_RS02125
Partner locus tags
HMPREF9550_RS02130HMPREF9550_RS02125
Partner old locus tags
HMPREF9550_04127HMPREF9550_04128
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_000673398.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9550_RS02125Primary locus identifier stored in the genes table.
Old locus tagHMPREF9550_04128Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772572.1Sequence record reported by the local genomic context database.
Genomic interval191 765-193 114 nt1 350 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span191 109-193 114 ntGCF_000164335::NZ_GG772572.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164335::NZ_GG772572.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772572.1All displayed genes belong to this local TCS context.
Neighborhood span191 109-193 114 nt2 006 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
191 109 nt193 114 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9550_RS02130GCF_000164335#HMPREF9550_RS02130
RROmpR
191 109-191 768 nt · Forward (+)
HMPREF9550_RS02125GCF_000164335#HMPREF9550_RS02125
HKClassicCurrent focus
191 765-193 114 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164335#HMPREF9550_RS02125The current gene is the representative for this cluster.
PFAM architecture2CSK_N + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1973333
Simplified PFAM architecture for HKOC_1973333
PFAM domain coverage: 297 / 449 aa (66.1%)
1 aa449 aa
2CSK_NHisKAHATPase_c
- Simplified architecture: 2CSK_N + HisKA + HATPase_c
- Raw architecture: 2CSK_N[23-157] | HisKA[237-301] | HATPase_c[349-445]
- Domain count: 3
- Matched identifier: HKOC_1973333
- Positioned domains: 2CSK_N 23-157 ; HisKA 237-301 ; HATPase_c 349-445
Cluster members and taxonomy
Representative gene: GCF_000164335#HMPREF9550_RS02125
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 547 · GCF_000164335
AssemblyASM16433v1 · Scaffoldhaploid
Genome composition4 403 159 bp · 51,0% GCEscherichia coli MS 187-1
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key