1 HAMP#1
167-236 aa · 70 aa · 15.0% of protein
Raw token
HAMP:167:5.62e-16:236:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9534_RS14610
Histidine kinase, Classic
Escherichia coli MS 69-1 · GCF_000164315
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164315#HMPREF9534_RS14610Stable P2CS identifier used across views.
GenomeGCF_000164315Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 467 aa (53.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
Domain-by-domain annotation3 items
2 HisKA#2
240-304 aa · 65 aa · 13.9% of protein
Raw token
HisKA:240:0.0000000000000102:304:65:643 HATPase_c#3
349-461 aa · 113 aa · 24.2% of protein
Raw token
HATPase_c:349:8.56e-29:461:113:109- Raw architecture: HAMP:167:5.62e-16:236:70:69#HisKA:240:0.0000000000000102:304:65:64#HATPase_c:349:8.56e-29:461:113:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164315::NZ_GG772397.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span119953-122075Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9534_02185RefSeq proteinWP_000675148.1
Context group ID
GCF_000164315::NZ_GG772397.1::G00029Context members
HMPREF9534_RS14615HMPREF9534_RS14610
Partner locus tags
HMPREF9534_RS14615HMPREF9534_RS14610
Partner old locus tags
HMPREF9534_02184HMPREF9534_02185
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000675148.1Primary protein accession used for annex mappings.
UniProt accessionB7NCB4Primary UniProt accession resolved in the annex database.
UniProt IDB7NCB4_ECOLUDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9534_RS14610Primary locus identifier stored in the genes table.
Old locus tagHMPREF9534_02185Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772397.1Sequence record reported by the local genomic context database.
Genomic interval120 672-122 075 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span119 953-122 075 ntGCF_000164315::NZ_GG772397.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164315::NZ_GG772397.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772397.1All displayed genes belong to this local TCS context.
Neighborhood span119 953-122 075 nt2 123 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 953 nt122 075 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9534_RS14615GCF_000164315#HMPREF9534_RS14615
RROmpR
119 953-120 675 nt · Reverse (-)
HMPREF9534_RS14610GCF_000164315#HMPREF9534_RS14610
HKClassicCurrent focus
120 672-122 075 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000026325#ECUMN_RS13090Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1747700
Simplified PFAM architecture for HKOC_1747700
PFAM domain coverage: 229 / 467 aa (49.0%)
1 aa467 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[184-235] | HisKA[240-304] | HATPase_c[349-460]
- Domain count: 3
- Matched identifier: HKOC_1747700
- Positioned domains: HAMP 184-235 ; HisKA 240-304 ; HATPase_c 349-460
Cluster members and taxonomy
Representative gene: GCF_000026325#ECUMN_RS13090
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 531 · GCF_000164315
AssemblyASM16431v1 · Scaffoldhaploid
Genome composition5 220 755 bp · 50,5% GCEscherichia coli MS 69-1
Signal transduction countsGenes 65 · HK 31 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key