Gene detail

HMPREF9534_RS11565

Histidine kinase, Classic

Escherichia coli MS 69-1 · GCF_000164315

ClassHKTypeClassicLength566 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164315#HMPREF9534_RS11565Stable P2CS identifier used across views.
GenomeGCF_000164315Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1228981Run 6 · 88 sequences · id 100% · cov 80% · representative
External referencesWP_001445869.1 · MIST4 HMPREF9534_RS11565RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length566 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage324 / 566 aa (57.2%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa566 aa
PilJ: 31-125 aa (95 aa)1HAMP: 150-224 aa (75 aa)2HisKA_3: 361-424 aa (64 aa)3HATPase_c: 467-556 aa (90 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
31-125 aa · 95 aa · 16.8% of protein
Raw tokenPilJ:31:3.9e-17:125:111:112
2 HAMP#2
150-224 aa · 75 aa · 13.3% of protein
Raw tokenHAMP:150:0.00000000000137:224:75:69
3 HisKA_3#3
361-424 aa · 64 aa · 11.3% of protein
Raw tokenHisKA_3:361:2.4e-17:424:64:68
4 HATPase_c#4
467-556 aa · 90 aa · 15.9% of protein
Raw tokenHATPase_c:467:2.25e-18:556:105:109
  • Raw architecture: PilJ:31:3.9e-17:125:111:112#HAMP:150:0.00000000000137:224:75:69#HisKA_3:361:2.4e-17:424:64:68#HATPase_c:467:2.25e-18:556:105:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000164315::NZ_GG772404.1::G00024
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span53273-54973Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9534_02879RefSeq proteinWP_001445869.1
Context group IDGCF_000164315::NZ_GG772404.1::G00024
Context members
HMPREF9534_RS11565
Partner locus tags
HMPREF9534_RS11565
Partner old locus tags
HMPREF9534_02879
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_001445869.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9534_RS11565Primary locus identifier stored in the genes table.
Old locus tagHMPREF9534_02879Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772404.1Sequence record reported by the local genomic context database.
Genomic interval53 273-54 973 nt1 701 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span53 273-54 973 ntGCF_000164315::NZ_GG772404.1::G00024

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164315::NZ_GG772404.1::G00024

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772404.1All displayed genes belong to this local TCS context.
Neighborhood span53 273-54 973 nt1 701 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
53 273 nt54 973 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1228981Run 6 · HK · 88 sequences
Representative sequenceGCF_000164315#HMPREF9534_RS11565The current gene is the representative for this cluster.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1228981

Simplified PFAM architecture for HKOC_1228981

PFAM domain coverage: 302 / 566 aa (53.4%)

1 aa566 aa
PilJ: 32-127 aaPilJHAMP: 172-223 aaHAMPHisKA_3: 361-424 aaHisKA_3HATPase_c: 467-556 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[32-127] | HAMP[172-223] | HisKA_3[361-424] | HATPase_c[467-556]
  • Domain count: 4
  • Matched identifier: HKOC_1228981
  • Positioned domains: PilJ 32-127 ; HAMP 172-223 ; HisKA_3 361-424 ; HATPase_c 467-556
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164315#HMPREF9534_RS11565

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 531 · GCF_000164315
AssemblyASM16431v1 · Scaffoldhaploid
Genome composition5 220 755 bp · 50,5% GCEscherichia coli MS 69-1
Signal transduction countsGenes 65 · HK 31 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key