Gene detail

HMPREF9534_RS11455

Histidine kinase, Hybrid

Escherichia coli MS 69-1 · GCF_000164315

ClassHKTypeHybridLength949 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164315#HMPREF9534_RS11455Stable P2CS identifier used across views.
GenomeGCF_000164315Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_0327722Run 6 · 1399 sequences · id 100% · cov 80% · representative
External referencesWP_000876029.1 · A0A7Z1I703 · MIST4 HMPREF9534_RS11455RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length949 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage286 / 949 aa (30.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa949 aa
HisKA: 469-534 aa (66 aa)1HATPase_c: 581-690 aa (110 aa)2Response_reg: 827-936 aa (110 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
469-534 aa · 66 aa · 7.0% of protein
Raw tokenHisKA:469:2.71e-17:534:66:64
2 HATPase_c#2
581-690 aa · 110 aa · 11.6% of protein
Raw tokenHATPase_c:581:1.64e-38:690:110:109
3 Response_reg#3
827-936 aa · 110 aa · 11.6% of protein
Raw tokenResponse_reg:827:3.97e-36:936:110:111
  • Raw architecture: HisKA:469:2.71e-17:534:66:64#HATPase_c:581:1.64e-38:690:110:109#Response_reg:827:3.97e-36:936:110:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000164315::NZ_GG772407.1::G00021
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span30987-33836Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9534_02904RefSeq proteinWP_000876029.1
Context group IDGCF_000164315::NZ_GG772407.1::G00021
Context members
HMPREF9534_RS11455
Partner locus tags
HMPREF9534_RS11455
Partner old locus tags
HMPREF9534_02904
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000876029.1Primary protein accession used for annex mappings.
UniProt accessionA0A7Z1I703Primary UniProt accession resolved in the annex database.
UniProt IDA0A7Z1I703_SHISODisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9534_RS11455Primary locus identifier stored in the genes table.
Old locus tagHMPREF9534_02904Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772407.1Sequence record reported by the local genomic context database.
Genomic interval30 987-33 836 nt2 850 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 987-33 836 ntGCF_000164315::NZ_GG772407.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164315::NZ_GG772407.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772407.1All displayed genes belong to this local TCS context.
Neighborhood span30 987-33 836 nt2 850 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 987 nt33 836 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0327722Run 6 · HK · 1399 sequences
Representative sequenceGCF_000164315#HMPREF9534_RS11455The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + RcsC + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0327722

Simplified PFAM architecture for HKOC_0327722

PFAM domain coverage: 376 / 949 aa (39.6%)

1 aa949 aa
HisKA: 470-534 aaHisKAHATPase_c: 581-690 aaHATPase_cRcsC: 709-799 aaRcsCResponse_reg: 827-936 aaResponse_reg
HisKAHATPase_cRcsCResponse_reg
  • Simplified architecture: HisKA + HATPase_c + RcsC + Response_reg
  • Raw architecture: HisKA[470-534] | HATPase_c[581-690] | RcsC[709-799] | Response_reg[827-936]
  • Domain count: 4
  • Matched identifier: HKOC_0327722
  • Positioned domains: HisKA 470-534 ; HATPase_c 581-690 ; RcsC 709-799 ; Response_reg 827-936
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164315#HMPREF9534_RS11455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 531 · GCF_000164315
AssemblyASM16431v1 · Scaffoldhaploid
Genome composition5 220 755 bp · 50,5% GCEscherichia coli MS 69-1
Signal transduction countsGenes 65 · HK 31 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key