Gene detail

HMPREF9536_RS12560

Response regulator, CheB family

Escherichia coli MS 84-1 · GCF_000164215

ClassRRTypeCheBLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164215#HMPREF9536_RS12560Stable P2CS identifier used across views.
GenomeGCF_000164215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterRROC_0481949Run 7 · 16270 sequences · id 100% · cov 80%
External referencesWP_000036371.1 · A0AAN4AXD3 · MIST4 HMPREF9536_RS12560RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regCheB_methylest
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage282 / 349 aa (80.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 CheB_methylestSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Response_reg: 6-108 aa (103 aa)1CheB_methylest: 159-337 aa (179 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
6-108 aa · 103 aa · 29.5% of protein
Raw tokenResponse_reg:6:7.87e-27:108:105:111
2 CheB_methylest#2
159-337 aa · 179 aa · 51.3% of protein
Raw tokenCheB_methylest:159:3.44e-91:337:180:177
  • Raw architecture: Response_reg:6:7.87e-27:108:105:111#CheB_methylest:159:3.44e-91:337:180:177
  • Domain description: 1 Response_reg,1 CheB_methylest
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164215::NZ_GG771630.1::G00018
Group size22 locus tags listed below.
HK / RR0 / 2Counts resolved for the local TCS neighborhood.
Context span276692-278145Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9536_02840RefSeq proteinWP_000036371.1
Context group IDGCF_000164215::NZ_GG771630.1::G00018
Context members
HMPREF9536_RS12565HMPREF9536_RS12560
Partner locus tags
HMPREF9536_RS12565HMPREF9536_RS12560
Partner old locus tags
HMPREF9536_02839HMPREF9536_02840
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000036371.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN4AXD3Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN4AXD3_SHIDYDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9536_RS12560Primary locus identifier stored in the genes table.
Old locus tagHMPREF9536_02840Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG771630.1Sequence record reported by the local genomic context database.
Genomic interval277 096-278 145 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span276 692-278 145 ntGCF_000164215::NZ_GG771630.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164215::NZ_GG771630.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG771630.1All displayed genes belong to this local TCS context.
Neighborhood span276 692-278 145 nt1 454 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
276 692 nt278 145 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9536_RS12565GCF_000164215#HMPREF9536_RS12565
RRCheY

276 692-277 081 nt · Reverse (-)

Old locus HMPREF9536_02839RefSeq WP_000763867.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0481949Run 7 · RR · 16270 sequences
Representative sequenceGCF_000007445#C_RS10880Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + CheB_methylest2 domains in the representative PFAM annotation.

PFAM architecture for RROC_0481949

Simplified PFAM architecture for RROC_0481949

PFAM domain coverage: 281 / 349 aa (80.5%)

1 aa349 aa
Response_reg: 6-108 aaResponse_regResponse_reg: 6-108 aaResponse_regCheB_methylest: 159-336 aaCheB_methylestCheB_methylest: 159-336 aaCheB_methylest
Response_regCheB_methylest
  • Simplified architecture: Response_reg + CheB_methylest
  • Raw architecture: Response_reg[6-108] | CheB_methylest[159-336]
  • Domain count: 2
  • Matched identifier: RROC_0481949
  • Positioned domains: Response_reg 6-108 ; Response_reg 6-108 ; CheB_methylest 159-336 ; CheB_methylest 159-336
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007445#C_RS10880

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 533 · GCF_000164215
AssemblyASM16421v1 · Scaffoldhaploid
Genome composition5 292 439 bp · 50,5% GCEscherichia coli MS 84-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key