Gene detail

HMPREF0220_RS17715

Histidine kinase, Classic

Clostridioides difficile NAP08 · GCF_000164175

ClassHKTypeClassicLength441 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164175#HMPREF0220_RS17715Stable P2CS identifier used across views.
GenomeGCF_000164175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2061447Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_003416114.1 · D5Q207 · MIST4 HMPREF0220_RS17715RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length441 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage340 / 441 aa (77.1%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa441 aa
HAMP: 6-74 aa (69 aa)1PAS_9: 96-195 aa (100 aa)2HisKA: 202-268 aa (67 aa)3HATPase_c: 319-422 aa (104 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
6-74 aa · 69 aa · 15.6% of protein
Raw tokenHAMP:6:0.00000048:74:69:69
2 PAS_9#2
96-195 aa · 100 aa · 22.7% of protein
Raw tokenPAS_9:96:0.00000111:195:103:102
3 HisKA#3
202-268 aa · 67 aa · 15.2% of protein
Raw tokenHisKA:202:2.75e-18:268:67:64
4 HATPase_c#4
319-422 aa · 104 aa · 23.6% of protein
Raw tokenHATPase_c:319:3.79e-30:422:104:109
  • Raw architecture: HAMP:6:0.00000048:74:69:69#PAS_9:96:0.00000111:195:103:102#HisKA:202:2.75e-18:268:67:64#HATPase_c:319:3.79e-30:422:104:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164175::NZ_GG770710.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span77472-79518Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0220_0939RefSeq proteinWP_003416114.1
Context group IDGCF_000164175::NZ_GG770710.1::G00039
Context members
HMPREF0220_RS17720HMPREF0220_RS17715
Partner locus tags
HMPREF0220_RS17720HMPREF0220_RS17715
Partner old locus tags
HMPREF0220_0938HMPREF0220_0939
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003416114.1Primary protein accession used for annex mappings.
UniProt accessionD5Q207Primary UniProt accession resolved in the annex database.
UniProt IDD5Q207_CLODIDisplay identifier provided by UniProt.
GO / PubMed6 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0220_RS17715Primary locus identifier stored in the genes table.
Old locus tagHMPREF0220_0939Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770710.1Sequence record reported by the local genomic context database.
Genomic interval78 193-79 518 nt1 326 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span77 472-79 518 ntGCF_000164175::NZ_GG770710.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164175::NZ_GG770710.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770710.1All displayed genes belong to this local TCS context.
Neighborhood span77 472-79 518 nt2 047 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
77 472 nt79 518 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0220_RS17720GCF_000164175#HMPREF0220_RS17720
RROmpR

77 472-78 164 nt · Forward (+)

Old locus HMPREF0220_0938RefSeq WP_003416112.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2061447Run 6 · HK · 1 sequences
Representative sequenceGCF_000164175#HMPREF0220_RS17715The current gene is the representative for this cluster.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2061447

Simplified PFAM architecture for HKOC_2061447

PFAM domain coverage: 324 / 441 aa (73.5%)

1 aa441 aa
HAMP: 30-74 aaHAMPPAS: 87-193 aaPASHisKA: 202-267 aaHisKAHATPase_c: 317-422 aaHATPase_c
HAMPPASHisKAHATPase_c
  • Simplified architecture: HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: HAMP[30-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
  • Domain count: 4
  • Matched identifier: HKOC_2061447
  • Positioned domains: HAMP 30-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164175#HMPREF0220_RS17715

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 1 over 1 total members. Page 1 / 1.

GCF_000164175#HMPREF0220_RS17715 (representative)
HMPREF0220_RS17715 · HK · Classic
RefSeq: WP_003416114.1
UniProt: D5Q207

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 259 · GCF_000164175
AssemblyASM16417v1 · Scaffoldhaploid
Genome composition4 078 686 bp · 29,0% GCClostridioides difficile NAP08
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key