Gene detail

HMPREF0220_RS15095

Histidine kinase, Classic

Clostridioides difficile NAP08 · GCF_000164175

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164175#HMPREF0220_RS15095Stable P2CS identifier used across views.
GenomeGCF_000164175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2216037Run 6 · 289 sequences · id 100% · cov 80%
External referencesWP_003424453.1 · D5Q3K1 · MIST4 HMPREF0220_RS15095RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
HisKA: 196-260 aa (65 aa)1HATPase_c: 307-424 aa (118 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000155:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:8.15e-19:424:119:109
  • Raw architecture: HisKA:196:0.0000000000155:260:65:64#HATPase_c:307:8.15e-19:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164175::NZ_GG770710.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span683625-685554Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0220_1483RefSeq proteinWP_003424453.1
Context group IDGCF_000164175::NZ_GG770710.1::G00046
Context members
HMPREF0220_RS15100HMPREF0220_RS15095
Partner locus tags
HMPREF0220_RS15100HMPREF0220_RS15095
Partner old locus tags
HMPREF0220_1482HMPREF0220_1483
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003424453.1Primary protein accession used for annex mappings.
UniProt accessionD5Q3K1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q3K1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0220_RS15095Primary locus identifier stored in the genes table.
Old locus tagHMPREF0220_1483Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770710.1Sequence record reported by the local genomic context database.
Genomic interval684 277-685 554 nt1 278 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span683 625-685 554 ntGCF_000164175::NZ_GG770710.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164175::NZ_GG770710.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770710.1All displayed genes belong to this local TCS context.
Neighborhood span683 625-685 554 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
683 625 nt685 554 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0220_RS15100GCF_000164175#HMPREF0220_RS15100
RROmpR

683 625-684 293 nt · Forward (+)

Old locus HMPREF0220_1482RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2216037Run 6 · HK · 289 sequences
Representative sequenceGCF_000155065#QAE_RS0210295Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2216037

Simplified PFAM architecture for HKOC_2216037

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2216037
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0210295

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 289 total members. Page 1 / 6.

GCF_000155065#QAE_RS0210295 (representative)
QAE_RS0210295 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_000164175#HMPREF0220_RS15095
HMPREF0220_RS15095 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_000164655#HMPREF0219_RS03830
HMPREF0219_RS03830 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_000210435#CDM120_RS10950
CDM120_RS10950 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_000499505#BN164_RS09820
BN164_RS09820 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_000582865#BN165_RS10460
BN165_RS10460 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_001050575#BN163_RS10675
BN163_RS10675 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_001972065#BER35_RS11195
BER35_RS11195 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_001972115#BER34_RS08685
BER34_RS08685 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002301695#BGU20_RS11405
BGU20_RS11405 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002302685#BGU93_RS07910
BGU93_RS07910 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002303305#BGU53_RS06380
BGU53_RS06380 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002352505#V439_RS01250
V439_RS01250 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002412385#V438_RS01340
V438_RS01340 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002946515#C4E25_RS11320
C4E25_RS11320 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002946535#C4E42_RS07870
C4E42_RS07870 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_002946555#C4E26_RS11320
C4E26_RS11320 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_003482165#CDIF29020_RS11665
CDIF29020_RS11665 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_003482365#CDIF29747_RS11190
CDIF29747_RS11190 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_003697245#EBL91_RS10600
EBL91_RS10600 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_004318565#E0Q96_RS10405
E0Q96_RS10405 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_004318785#E0Q93_RS04815
E0Q93_RS04815 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_008579085#F6C11_RS11710
F6C11_RS11710 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_009362915#FTB24_RS08190
FTB24_RS08190 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_012952655#HCN89_RS11340
HCN89_RS11340 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_015351855#ITI91_RS10895
ITI91_RS10895 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_015352255#ITJ05_RS13015
ITJ05_RS13015 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016766955#JMW53_RS00230
JMW53_RS00230 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016766975#JMW50_RS07520
JMW50_RS07520 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016766995#JMW52_RS10060
JMW52_RS10060 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016767015#JMW49_RS15915
JMW49_RS15915 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016767035#JMW55_RS12875
JMW55_RS12875 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016767055#JMW51_RS10315
JMW51_RS10315 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016767095#JMW48_RS04050
JMW48_RS04050 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016767115#JMW47_RS00625
JMW47_RS00625 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_016767135#JMW46_RS01990
JMW46_RS01990 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_017592625#J5O10_RS10945
J5O10_RS10945 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_018603395#KK111_RS10660
KK111_RS10660 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_018603455#KK110_RS10650
KK110_RS10650 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_018603475#KK112_RS10630
KK112_RS10630 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_018884725#E1H40_RS10350
E1H40_RS10350 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_019427665#K1N48_RS16275
K1N48_RS16275 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_019427725#K1N54_RS14905
K1N54_RS14905 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_020297505#LA365_RS01815
LA365_RS01815 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_021283625#LWE91_RS13520
LWE91_RS13520 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_021283665#LWF03_RS12920
LWF03_RS12920 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_021283685#LWE71_RS10865
LWE71_RS10865 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_021283745#LWE78_RS13545
LWE78_RS13545 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_021283845#LWG76_RS11690
LWG76_RS11690 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1
GCF_021283885#LWE86_RS15810
LWE86_RS15810 · HK · Classic
RefSeq: WP_003424453.1
UniProt: D5Q3K1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 259 · GCF_000164175
AssemblyASM16417v1 · Scaffoldhaploid
Genome composition4 078 686 bp · 29,0% GCClostridioides difficile NAP08
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key