Gene detail

HMPREF0220_RS08610

Response regulator, PleD family

Clostridioides difficile NAP08 · GCF_000164175

ClassRRTypePleDLength319 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164175#HMPREF0220_RS08610Stable P2CS identifier used across views.
GenomeGCF_000164175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0533521Run 7 · 304 sequences · id 100% · cov 80%
External referencesWP_003417901.1 · D5Q0C6 · MIST4 HMPREF0220_RS08610RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regGGDEF
Protein length319 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage267 / 319 aa (83.7%)Merged over positioned domains only.
Domain description1 Response_reg,1 GGDEFSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa319 aa
Response_reg: 9-120 aa (112 aa)1GGDEF: 153-307 aa (155 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
9-120 aa · 112 aa · 35.1% of protein
Raw tokenResponse_reg:9:1.21e-27:120:112:111
2 GGDEF#2
153-307 aa · 155 aa · 48.6% of protein
Raw tokenGGDEF:153:8.36e-46:307:158:160
  • Raw architecture: Response_reg:9:1.21e-27:120:112:111#GGDEF:153:8.36e-46:307:158:160
  • Domain description: 1 Response_reg,1 GGDEF
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000164175::NZ_GG770712.1::G00020
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span232889-233848Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0220_0358RefSeq proteinWP_003417901.1
Context group IDGCF_000164175::NZ_GG770712.1::G00020
Context members
HMPREF0220_RS08610
Partner locus tags
HMPREF0220_RS08610
Partner old locus tags
HMPREF0220_0358
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003417901.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0C6Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0C6_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0220_RS08610Primary locus identifier stored in the genes table.
Old locus tagHMPREF0220_0358Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770712.1Sequence record reported by the local genomic context database.
Genomic interval232 889-233 848 nt960 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span232 889-233 848 ntGCF_000164175::NZ_GG770712.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164175::NZ_GG770712.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770712.1All displayed genes belong to this local TCS context.
Neighborhood span232 889-233 848 nt960 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
232 889 nt233 848 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0533521Run 7 · RR · 304 sequences
Representative sequenceGCF_000155065#QAE_RS0202590Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GGDEF2 domains in the representative PFAM annotation.

PFAM architecture for RROC_0533521

Simplified PFAM architecture for RROC_0533521

PFAM domain coverage: 266 / 319 aa (83.4%)

1 aa319 aa
Response_reg: 9-120 aaResponse_regResponse_reg: 9-120 aaResponse_regGGDEF: 153-306 aaGGDEFGGDEF: 153-306 aaGGDEF
Response_regGGDEF
  • Simplified architecture: Response_reg + GGDEF
  • Raw architecture: Response_reg[9-120] | GGDEF[153-306]
  • Domain count: 2
  • Matched identifier: RROC_0533521
  • Positioned domains: Response_reg 9-120 ; Response_reg 9-120 ; GGDEF 153-306 ; GGDEF 153-306
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202590

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 304 total members. Page 1 / 7.

GCF_000155065#QAE_RS0202590 (representative)
QAE_RS0202590 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_000164175#HMPREF0220_RS08610
HMPREF0220_RS08610 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_000164655#HMPREF0219_RS16850
HMPREF0219_RS16850 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_000210435#CDM120_RS03420
CDM120_RS03420 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_000499505#BN164_RS02925
BN164_RS02925 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_000531165#BN166_RS14190
BN166_RS14190 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_000582865#BN165_RS02530
BN165_RS02530 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_001050575#BN163_RS02575
BN163_RS02575 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_001972065#BER35_RS03570
BER35_RS03570 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_001972115#BER34_RS16410
BER34_RS16410 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002301695#BGU20_RS05655
BGU20_RS05655 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002302685#BGU93_RS13935
BGU93_RS13935 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002303305#BGU53_RS09335
BGU53_RS09335 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002303425#BGU60_RS15855
BGU60_RS15855 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002352505#V439_RS14300
V439_RS14300 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002412385#V438_RS10080
V438_RS10080 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002946515#C4E25_RS02950
C4E25_RS02950 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002946535#C4E42_RS16235
C4E42_RS16235 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_002946555#C4E26_RS02950
C4E26_RS02950 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_003482165#CDIF29020_RS03195
CDIF29020_RS03195 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_003482365#CDIF29747_RS02950
CDIF29747_RS02950 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_003697205#EBB60_RS03390
EBB60_RS03390 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_003697225#EBL90_RS03535
EBL90_RS03535 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_003697245#EBL91_RS02940
EBL91_RS02940 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_004318565#E0Q96_RS13210
E0Q96_RS13210 · RR · PleD
RefSeq: WP_131040775.1
GCF_004318565#E0Q96_RS16055
E0Q96_RS16055 · RR · CheY
RefSeq: WP_131040843.1
GCF_004318785#E0Q93_RS10175
E0Q93_RS10175 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_008579085#F6C11_RS03885
F6C11_RS03885 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_009362915#FTB24_RS15980
FTB24_RS15980 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_012952655#HCN89_RS02775
HCN89_RS02775 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_015351855#ITI91_RS03450
ITI91_RS03450 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_015352255#ITJ05_RS13750
ITJ05_RS13750 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_015732535#CDIF101085_RS03050
CDIF101085_RS03050 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016766955#JMW53_RS11290
JMW53_RS11290 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016766975#JMW50_RS18060
JMW50_RS18060 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016766995#JMW52_RS17740
JMW52_RS17740 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016767015#JMW49_RS05445
JMW49_RS05445 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016767035#JMW55_RS02395
JMW55_RS02395 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016767055#JMW51_RS17665
JMW51_RS17665 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016767095#JMW48_RS12030
JMW48_RS12030 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016767115#JMW47_RS08490
JMW47_RS08490 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_016767135#JMW46_RS12500
JMW46_RS12500 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_017592625#J5O10_RS02910
J5O10_RS02910 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_018603395#KK111_RS03165
KK111_RS03165 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_018603455#KK110_RS03160
KK110_RS03160 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_018603475#KK112_RS03160
KK112_RS03160 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_018884725#E1H40_RS02880
E1H40_RS02880 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_019427665#K1N48_RS08990
K1N48_RS08990 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_019427725#K1N54_RS06840
K1N54_RS06840 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6
GCF_019931025#K8P06_RS13795
K8P06_RS13795 · RR · PleD
RefSeq: WP_003417901.1
UniProt: D5Q0C6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 259 · GCF_000164175
AssemblyASM16417v1 · Scaffoldhaploid
Genome composition4 078 686 bp · 29,0% GCClostridioides difficile NAP08
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key