1 Response_reg#1
11-125 aa · 115 aa · 42.0% of protein
Raw token
Response_reg:11:3.16e-23:125:115:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0220_RS05795
Response regulator Spo0A family
Clostridioides difficile NAP08 · GCF_000164175
ClassRRTypeSpo0ALength274 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164175#HMPREF0220_RS05795Stable P2CS identifier used across views.
GenomeGCF_000164175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regSpo0A_C
Protein length274 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage219 / 274 aa (79.9%)Merged over positioned domains only.
Domain description1 Response_reg,1 Spo0A_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa274 aa
Domain-by-domain annotation2 items
2 Spo0A_C#2
163-266 aa · 104 aa · 38.0% of protein
Raw token
Spo0A_C:163:7.55e-66:266:104:104- Raw architecture: Response_reg:11:3.16e-23:125:115:111#Spo0A_C:163:7.55e-66:266:104:104
- Domain description: 1 Response_reg,1 Spo0A_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000164175::NZ_GG770713.1::G00005
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span167481-168305Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0220_2190RefSeq proteinWP_003419197.1
Context group ID
GCF_000164175::NZ_GG770713.1::G00005Context members
HMPREF0220_RS05795
Partner locus tags
HMPREF0220_RS05795
Partner old locus tags
HMPREF0220_2190
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003419197.1Primary protein accession used for annex mappings.
UniProt accessionD5Q5K8Primary UniProt accession resolved in the annex database.
UniProt IDD5Q5K8_CLODIDisplay identifier provided by UniProt.
GO / PubMed9 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0220_RS05795Primary locus identifier stored in the genes table.
Old locus tagHMPREF0220_2190Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770713.1Sequence record reported by the local genomic context database.
Genomic interval167 481-168 305 nt825 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span167 481-168 305 ntGCF_000164175::NZ_GG770713.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164175::NZ_GG770713.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770713.1All displayed genes belong to this local TCS context.
Neighborhood span167 481-168 305 nt825 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
167 481 nt168 305 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF0220_RS05795GCF_000164175#HMPREF0220_RS05795
RRSpo0ACurrent focus
167 481-168 305 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164175#HMPREF0220_RS05795The current gene is the representative for this cluster.
PFAM architectureResponse_reg + Spo0A_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0606287
Simplified PFAM architecture for RROC_0606287
PFAM domain coverage: 218 / 274 aa (79.6%)
1 aa274 aa
Response_regSpo0A_C
- Simplified architecture: Response_reg + Spo0A_C
- Raw architecture: Response_reg[11-124] | Spo0A_C[163-266]
- Domain count: 2
- Matched identifier: RROC_0606287
- Positioned domains: Response_reg 11-124 ; Response_reg 11-124 ; Spo0A_C 163-266 ; Spo0A_C 163-266
Cluster members and taxonomy
Representative gene: GCF_000164175#HMPREF0220_RS05795
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 525 259 · GCF_000164175
AssemblyASM16417v1 · Scaffoldhaploid
Genome composition4 078 686 bp · 29,0% GCClostridioides difficile NAP08
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key