Gene detail

HMPREF9377_RS11075

Histidine kinase, Classic

Enterococcus faecalis R712 · GCF_000163815

ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000163815#HMPREF9377_RS11075Stable P2CS identifier used across views.
GenomeGCF_000163815Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1182891Run 6 · 42 sequences · id 100% · cov 80%
External referencesWP_002390920.1 · MIST4 HMPREF9377_RS11075RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 576 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
HAMP: 288-360 aa (73 aa)1His_kinase: 375-453 aa (79 aa)2HATPase_c: 464-574 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-360 aa · 73 aa · 12.7% of protein
Raw tokenHAMP:288:0.0000000821:360:73:69
2 His_kinase#2
375-453 aa · 79 aa · 13.7% of protein
Raw tokenHis_kinase:375:6.36e-28:453:80:80
3 HATPase_c#3
464-574 aa · 111 aa · 19.3% of protein
Raw tokenHATPase_c:464:0.0000000000197:574:113:109
  • Raw architecture: HAMP:288:0.0000000821:360:73:69#His_kinase:375:6.36e-28:453:80:80#HATPase_c:464:0.0000000000197:574:113:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000163815::NZ_GG739851.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span151261-154484Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9377_01528RefSeq proteinWP_002390920.1
Context group IDGCF_000163815::NZ_GG739851.1::G00008
Context members
HMPREF9377_RS11075HMPREF9377_RS11080
Partner locus tags
HMPREF9377_RS11075HMPREF9377_RS11080
Partner old locus tags
HMPREF9377_01528HMPREF9377_01529
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002390920.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9377_RS11075Primary locus identifier stored in the genes table.
Old locus tagHMPREF9377_01528Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG739851.1Sequence record reported by the local genomic context database.
Genomic interval151 261-152 991 nt1 731 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span151 261-154 484 ntGCF_000163815::NZ_GG739851.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000163815::NZ_GG739851.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG739851.1All displayed genes belong to this local TCS context.
Neighborhood span151 261-154 484 nt3 224 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
151 261 nt154 484 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9377_RS11080GCF_000163815#HMPREF9377_RS11080
RRunclassified

153 003-154 484 nt · Forward (+)

Old locus HMPREF9377_01529RefSeq WP_002369015.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1182891Run 6 · HK · 42 sequences
Representative sequenceGCF_000147985#HMPREF9493_RS06575Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1182891

Simplified PFAM architecture for HKOC_1182891

PFAM domain coverage: 180 / 576 aa (31.3%)

1 aa576 aa
His_kinase: 375-453 aaHis_kinaseHATPase_c: 474-574 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[375-453] | HATPase_c[474-574]
  • Domain count: 2
  • Matched identifier: HKOC_1182891
  • Positioned domains: His_kinase 375-453 ; HATPase_c 474-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147985#HMPREF9493_RS06575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 186 · GCF_000163815
AssemblyASM16381v1 · Scaffoldhaploid
Genome composition3 039 544 bp · 37,5% GCEnterococcus faecalis R712
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key