Gene detail

HMPREF9376_RS04125

Histidine kinase, Classic

Enterococcus faecalis S613 · GCF_000163795

ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000163795#HMPREF9376_RS04125Stable P2CS identifier used across views.
GenomeGCF_000163795Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2082206Run 6 · 307 sequences · id 100% · cov 80%
External referencesWP_002383089.1 · Q833S3 · MIST4 HMPREF9376_RS04125RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 439 aa (48.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
HAMP: 144-211 aa (68 aa)1HisKA: 232-296 aa (65 aa)2HATPase_c: 342-419 aa (78 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 15.5% of protein
Raw tokenHAMP:144:0.00000231:211:70:69
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw tokenHisKA:232:0.0000038:296:65:64
3 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw tokenHATPase_c:342:0.00000544:419:90:109
  • Raw architecture: HAMP:144:0.00000231:211:70:69#HisKA:232:0.0000038:296:65:64#HATPase_c:342:0.00000544:419:90:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000163795::NZ_GG739726.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5151-7120Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9376_00101RefSeq proteinWP_002383089.1
Context group IDGCF_000163795::NZ_GG739726.1::G00017
Context members
HMPREF9376_RS04125HMPREF9376_RS04130
Partner locus tags
HMPREF9376_RS04125HMPREF9376_RS04130
Partner old locus tags
HMPREF9376_00101HMPREF9376_00102
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002383089.1Primary protein accession used for annex mappings.
UniProt accessionQ833S3Primary UniProt accession resolved in the annex database.
UniProt IDQ833S3_ENTFADisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9376_RS04125Primary locus identifier stored in the genes table.
Old locus tagHMPREF9376_00101Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG739726.1Sequence record reported by the local genomic context database.
Genomic interval5 151-6 470 nt1 320 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 151-7 120 ntGCF_000163795::NZ_GG739726.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000163795::NZ_GG739726.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG739726.1All displayed genes belong to this local TCS context.
Neighborhood span5 151-7 120 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 151 nt7 120 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9376_RS04130GCF_000163795#HMPREF9376_RS04130
RROmpR

6 467-7 120 nt · Reverse (-)

Old locus HMPREF9376_00102RefSeq WP_002285815.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2082206Run 6 · HK · 307 sequences
Representative sequenceGCF_000007785#EF_RS08940Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2082206

Simplified PFAM architecture for HKOC_2082206

PFAM domain coverage: 147 / 439 aa (33.5%)

1 aa439 aa
HisKA: 233-296 aaHisKAHATPase_c: 342-424 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-296] | HATPase_c[342-424]
  • Domain count: 2
  • Matched identifier: HKOC_2082206
  • Positioned domains: HisKA 233-296 ; HATPase_c 342-424
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007785#EF_RS08940

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 185 · GCF_000163795
AssemblyASM16379v1 · Scaffoldhaploid
Genome composition3 047 348 bp · 37,5% GCEnterococcus faecalis S613
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key