1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw token
HisKA:237:0.00000000000115:299:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECGG_RS00225
Histidine kinase, Classic
Escherichia coli FVEC1412 · GCF_000163235
ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000163235#ECGG_RS00225Stable P2CS identifier used across views.
GenomeGCF_000163235Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw token
HATPase_c:345:5.81e-34:451:110:109- Raw architecture: HisKA:237:0.00000000000115:299:63:64#HATPase_c:345:5.81e-34:451:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000163235::NZ_GG749233.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30412-33110Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECGG_04892RefSeq proteinWP_001211912.1
Context group ID
GCF_000163235::NZ_GG749233.1::G00001Context members
ECGG_RS00225ECGG_RS00220
Partner locus tags
ECGG_RS00225ECGG_RS00220
Partner old locus tags
ECGG_04892ECGG_04893
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001211912.1Primary protein accession used for annex mappings.
UniProt accessionB7NFU4Primary UniProt accession resolved in the annex database.
UniProt IDB7NFU4_ECOLUDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECGG_RS00225Primary locus identifier stored in the genes table.
Old locus tagECGG_04892Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG749233.1Sequence record reported by the local genomic context database.
Genomic interval30 412-31 788 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 412-33 110 ntGCF_000163235::NZ_GG749233.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000163235::NZ_GG749233.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG749233.1All displayed genes belong to this local TCS context.
Neighborhood span30 412-33 110 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 412 nt33 110 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECGG_RS00225GCF_000163235#ECGG_RS00225
HKClassicCurrent focus
30 412-31 788 nt · Forward (+)
ECGG_RS00220GCF_000163235#ECGG_RS00220
RRNtrC
31 785-33 110 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000026325#ECUMN_RS23495Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1858349
Simplified PFAM architecture for HKOC_1858349
PFAM domain coverage: 168 / 458 aa (36.7%)
1 aa458 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[238-300] | HATPase_c[346-450]
- Domain count: 2
- Matched identifier: HKOC_1858349
- Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Representative gene: GCF_000026325#ECUMN_RS23495
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 656 380 · GCF_000163235
AssemblyASM16323v1 · Scaffoldhaploid
Genome composition5 234 178 bp · 50,5% GCEscherichia coli FVEC1412
Signal transduction countsGenes 58 · HK 27 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key