Gene detail

ECFG_RS14895

Histidine kinase, Classic

Escherichia coli FVEC1302 · GCF_000163215

ClassHKTypeClassicLength598 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000163215#ECFG_RS14895Stable P2CS identifier used across views.
GenomeGCF_000163215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1061577Run 6 · 1037 sequences · id 100% · cov 80%
External referencesWP_000918083.1 · D3H2K8 · MIST4 ECFG_RS14895RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length598 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage314 / 598 aa (52.5%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa598 aa
PilJ: 35-128 aa (94 aa)1HAMP: 158-225 aa (68 aa)2HisKA_3: 390-453 aa (64 aa)3HATPase_c: 496-583 aa (88 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
35-128 aa · 94 aa · 15.7% of protein
Raw tokenPilJ:35:0.0000000158:128:112:112
2 HAMP#2
158-225 aa · 68 aa · 11.4% of protein
Raw tokenHAMP:158:0.0000000000574:225:69:69
3 HisKA_3#3
390-453 aa · 64 aa · 10.7% of protein
Raw tokenHisKA_3:390:2.12e-17:453:64:68
4 HATPase_c#4
496-583 aa · 88 aa · 14.7% of protein
Raw tokenHATPase_c:496:4.97e-20:583:103:109
  • Raw architecture: PilJ:35:0.0000000158:128:112:112#HAMP:158:0.0000000000574:225:69:69#HisKA_3:390:2.12e-17:453:64:68#HATPase_c:496:4.97e-20:583:103:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000163215::NZ_GG774912.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span92234-94673Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECFG_00100RefSeq proteinWP_000918083.1
Context group IDGCF_000163215::NZ_GG774912.1::G00009
Context members
ECFG_RS14900ECFG_RS14895
Partner locus tags
ECFG_RS14900ECFG_RS14895
Partner old locus tags
ECFG_00099ECFG_00100
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000918083.1Primary protein accession used for annex mappings.
UniProt accessionD3H2K8Primary UniProt accession resolved in the annex database.
UniProt IDD3H2K8_ECO44Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECFG_RS14895Primary locus identifier stored in the genes table.
Old locus tagECFG_00100Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774912.1Sequence record reported by the local genomic context database.
Genomic interval92 877-94 673 nt1 797 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span92 234-94 673 ntGCF_000163215::NZ_GG774912.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000163215::NZ_GG774912.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774912.1All displayed genes belong to this local TCS context.
Neighborhood span92 234-94 673 nt2 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
92 234 nt94 673 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECFG_RS14900GCF_000163215#ECFG_RS14900
RRNarL

92 234-92 884 nt · Reverse (-)

Old locus ECFG_00099RefSeq WP_000070487.1
ECFG_RS14895GCF_000163215#ECFG_RS14895
HKClassicCurrent focus

92 877-94 673 nt · Reverse (-)

Old locus ECFG_00100RefSeq WP_000918083.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1061577Run 6 · HK · 1037 sequences
Representative sequenceGCF_000026325#ECUMN_RS08590Use this link to inspect the representative gene detail.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1061577

Simplified PFAM architecture for HKOC_1061577

PFAM domain coverage: 299 / 598 aa (50.0%)

1 aa598 aa
PilJ: 35-127 aaPilJHAMP: 173-224 aaHAMPHisKA_3: 390-453 aaHisKA_3HATPase_c: 496-585 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[35-127] | HAMP[173-224] | HisKA_3[390-453] | HATPase_c[496-585]
  • Domain count: 4
  • Matched identifier: HKOC_1061577
  • Positioned domains: PilJ 35-127 ; HAMP 173-224 ; HisKA_3 390-453 ; HATPase_c 496-585
Cluster members and taxonomy
Visualization

Representative gene: GCF_000026325#ECUMN_RS08590

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 656 379 · GCF_000163215
AssemblyASM16321v1 · Scaffoldhaploid
Genome composition5 339 642 bp · 50,5% GCEscherichia coli FVEC1302
Signal transduction countsGenes 60 · HK 28 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key