1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw token
HAMP:165:0.000000000000986:234:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECFG_RS00725
Histidine kinase, Classic
Escherichia coli FVEC1302 · GCF_000163215
ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000163215#ECFG_RS00725Stable P2CS identifier used across views.
GenomeGCF_000163215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw token
HisKA:238:8.29e-17:299:63:643 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw token
HATPase_c:345:1.16e-29:453:110:109- Raw architecture: HAMP:165:0.000000000000986:234:70:69#HisKA:238:8.29e-17:299:63:64#HATPase_c:345:1.16e-29:453:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000163215::NZ_GG774918.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span64273-66341Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECFG_04779RefSeq proteinWP_000580422.1
Context group ID
GCF_000163215::NZ_GG774918.1::G00003Context members
ECFG_RS00725ECFG_RS00720
Partner locus tags
ECFG_RS00725ECFG_RS00720
Partner old locus tags
ECFG_04779ECFG_04780
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000580422.1Primary protein accession used for annex mappings.
UniProt accessionD3GRW8Primary UniProt accession resolved in the annex database.
UniProt IDD3GRW8_ECO44Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECFG_RS00725Primary locus identifier stored in the genes table.
Old locus tagECFG_04779Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774918.1Sequence record reported by the local genomic context database.
Genomic interval64 273-65 646 nt1 374 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span64 273-66 341 ntGCF_000163215::NZ_GG774918.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000163215::NZ_GG774918.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774918.1All displayed genes belong to this local TCS context.
Neighborhood span64 273-66 341 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
64 273 nt66 341 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECFG_RS00725GCF_000163215#ECFG_RS00725
HKClassicCurrent focus
64 273-65 646 nt · Reverse (-)
ECFG_RS00720GCF_000163215#ECFG_RS00720
RROmpR
65 643-66 341 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000026325#ECUMN_RS23025Use this link to inspect the representative gene detail.
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1873423
Simplified PFAM architecture for HKOC_1873423
PFAM domain coverage: 293 / 457 aa (64.1%)
1 aa457 aa
CpxA_periHAMPHisKAHATPase_c
- Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
- Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
- Domain count: 4
- Matched identifier: HKOC_1873423
- Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Representative gene: GCF_000026325#ECUMN_RS23025
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 656 379 · GCF_000163215
AssemblyASM16321v1 · Scaffoldhaploid
Genome composition5 339 642 bp · 50,5% GCEscherichia coli FVEC1302
Signal transduction countsGenes 60 · HK 28 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key