Gene detail

ECFG_RS00275

Histidine kinase, Classic

Escherichia coli FVEC1302 · GCF_000163215

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000163215#ECFG_RS00275Stable P2CS identifier used across views.
GenomeGCF_000163215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1858349Run 6 · 1044 sequences · id 100% · cov 80%
External referencesWP_001211912.1 · B7NFU4 · MIST4 ECFG_RS00275RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
HisKA: 237-299 aa (63 aa)1HATPase_c: 345-451 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw tokenHisKA:237:0.00000000000115:299:63:64
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw tokenHATPase_c:345:5.81e-34:451:110:109
  • Raw architecture: HisKA:237:0.00000000000115:299:63:64#HATPase_c:345:5.81e-34:451:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000163215::NZ_GG774919.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30673-33371Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECFG_05046RefSeq proteinWP_001211912.1
Context group IDGCF_000163215::NZ_GG774919.1::G00001
Context members
ECFG_RS00275ECFG_RS00270
Partner locus tags
ECFG_RS00275ECFG_RS00270
Partner old locus tags
ECFG_05046ECFG_05047
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001211912.1Primary protein accession used for annex mappings.
UniProt accessionB7NFU4Primary UniProt accession resolved in the annex database.
UniProt IDB7NFU4_ECOLUDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECFG_RS00275Primary locus identifier stored in the genes table.
Old locus tagECFG_05046Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774919.1Sequence record reported by the local genomic context database.
Genomic interval30 673-32 049 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 673-33 371 ntGCF_000163215::NZ_GG774919.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000163215::NZ_GG774919.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774919.1All displayed genes belong to this local TCS context.
Neighborhood span30 673-33 371 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 673 nt33 371 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECFG_RS00275GCF_000163215#ECFG_RS00275
HKClassicCurrent focus

30 673-32 049 nt · Forward (+)

Old locus ECFG_05046RefSeq WP_001211912.1
ECFG_RS00270GCF_000163215#ECFG_RS00270
RRNtrC

32 046-33 371 nt · Forward (+)

Old locus ECFG_05047RefSeq WP_000148522.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858349Run 6 · HK · 1044 sequences
Representative sequenceGCF_000026325#ECUMN_RS23495Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858349

Simplified PFAM architecture for HKOC_1858349

PFAM domain coverage: 168 / 458 aa (36.7%)

1 aa458 aa
HisKA: 238-300 aaHisKAHATPase_c: 346-450 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[238-300] | HATPase_c[346-450]
  • Domain count: 2
  • Matched identifier: HKOC_1858349
  • Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Visualization

Representative gene: GCF_000026325#ECUMN_RS23495

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 656 379 · GCF_000163215
AssemblyASM16321v1 · Scaffoldhaploid
Genome composition5 339 642 bp · 50,5% GCEscherichia coli FVEC1302
Signal transduction countsGenes 60 · HK 28 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key