Gene detail

EFXG_RS06475

Histidine kinase, Classic

Enterococcus faecium C68 · GCF_000160315

ClassHKTypeClassicLength447 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000160315#EFXG_RS06475Stable P2CS identifier used across views.
GenomeGCF_000160315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1999551Run 6 · 25 sequences · id 100% · cov 80% · representative
External referencesWP_002317272.1 · A0A132PA59 · MIST4 EFXG_RS06475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length447 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage244 / 447 aa (54.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa447 aa
HAMP: 138-205 aa (68 aa)1HisKA: 224-289 aa (66 aa)2HATPase_c: 335-444 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
138-205 aa · 68 aa · 15.2% of protein
Raw tokenHAMP:138:0.00000000000194:205:68:69
2 HisKA#2
224-289 aa · 66 aa · 14.8% of protein
Raw tokenHisKA:224:0.00000000133:289:66:64
3 HATPase_c#3
335-444 aa · 110 aa · 24.6% of protein
Raw tokenHATPase_c:335:2.89e-17:444:111:109
  • Raw architecture: HAMP:138:0.00000000000194:205:68:69#HisKA:224:0.00000000133:289:66:64#HATPase_c:335:2.89e-17:444:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000160315::NZ_ACJQ02000002.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span89026-91031Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFXG_01485RefSeq proteinWP_002317272.1
Context group IDGCF_000160315::NZ_ACJQ02000002.1::G00006
Context members
EFXG_RS06470EFXG_RS06475
Partner locus tags
EFXG_RS06470EFXG_RS06475
Partner old locus tags
EFXG_01486EFXG_01485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002317272.1Primary protein accession used for annex mappings.
UniProt accessionA0A132PA59Primary UniProt accession resolved in the annex database.
UniProt IDA0A132PA59_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFXG_RS06475Primary locus identifier stored in the genes table.
Old locus tagEFXG_01485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ACJQ02000002.1Sequence record reported by the local genomic context database.
Genomic interval89 688-91 031 nt1 344 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span89 026-91 031 ntGCF_000160315::NZ_ACJQ02000002.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000160315::NZ_ACJQ02000002.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ACJQ02000002.1All displayed genes belong to this local TCS context.
Neighborhood span89 026-91 031 nt2 006 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
89 026 nt91 031 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFXG_RS06470GCF_000160315#EFXG_RS06470
RROmpR

89 026-89 685 nt · Forward (+)

Old locus EFXG_01486RefSeq WP_002317273.1
EFXG_RS06475GCF_000160315#EFXG_RS06475
HKClassicCurrent focus

89 688-91 031 nt · Forward (+)

Old locus EFXG_01485RefSeq WP_002317272.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1999551Run 6 · HK · 25 sequences
Representative sequenceGCF_000160315#EFXG_RS06475The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1999551

Simplified PFAM architecture for HKOC_1999551

PFAM domain coverage: 225 / 447 aa (50.3%)

1 aa447 aa
HAMP: 155-204 aaHAMPHisKA: 224-288 aaHisKAHATPase_c: 335-444 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[155-204] | HisKA[224-288] | HATPase_c[335-444]
  • Domain count: 3
  • Matched identifier: HKOC_1999551
  • Positioned domains: HAMP 155-204 ; HisKA 224-288 ; HATPase_c 335-444
Cluster members and taxonomy
Visualization

Representative gene: GCF_000160315#EFXG_RS06475

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 664 · GCF_000160315
AssemblyEFCM_C68_V3 · Contighaploid
Genome composition2 957 107 bp · 38,0% GCEnterococcus faecium C68
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key