Gene detail

HMPREF0346_RS04695

Histidine kinase, Classic

Enterococcus faecalis EnGen0297 · GCF_000160155

ClassHKTypeClassicLength609 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000160155#HMPREF0346_RS04695Stable P2CS identifier used across views.
GenomeGCF_000160155Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1008540Run 6 · 419 sequences · id 100% · cov 80%
External referencesWP_002379340.1 · A0ABC9TMZ7 · MIST4 HMPREF0346_RS04695RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length609 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 609 aa (58.8%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF0346_RS04695
Domain-by-domain annotation4 items
1 HAMP#1
180-249 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:180:8.77e-19:249:70:69
2 PAS#2
259-366 aa · 108 aa · 17.7% of protein
Raw tokenPAS:259:0.0000000000946:366:115:113
3 HisKA#3
375-442 aa · 68 aa · 11.2% of protein
Raw tokenHisKA:375:3.55e-19:442:68:64
4 HATPase_c#4
491-602 aa · 112 aa · 18.4% of protein
Raw tokenHATPase_c:491:4.1e-33:602:112:109
  • Raw architecture: HAMP:180:8.77e-19:249:70:69#PAS:259:0.0000000000946:366:115:113#HisKA:375:3.55e-19:442:68:64#HATPase_c:491:4.1e-33:602:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000160155::NZ_GG668819.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span137305-139845Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0346_0143RefSeq proteinWP_002379340.1
Context group IDGCF_000160155::NZ_GG668819.1::G00010
Context members
HMPREF0346_RS04690HMPREF0346_RS04695
Partner locus tags
HMPREF0346_RS04690HMPREF0346_RS04695
Partner old locus tags
HMPREF0346_0142HMPREF0346_0143
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002379340.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9TMZ7Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9TMZ7_ENTFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0346_RS04695Primary locus identifier stored in the genes table.
Old locus tagHMPREF0346_0143Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG668819.1Sequence record reported by the local genomic context database.
Genomic interval138 016-139 845 nt1 830 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span137 305-139 845 ntGCF_000160155::NZ_GG668819.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000160155::NZ_GG668819.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG668819.1All displayed genes belong to this local TCS context.
Neighborhood span137 305-139 845 nt2 541 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
137 305 nt139 845 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0346_RS04690GCF_000160155#HMPREF0346_RS04690
RROmpR

137 305-138 009 nt · Forward (+)

Old locus HMPREF0346_0142RefSeq WP_002357947.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1008540Run 6 · HK · 419 sequences
Representative sequenceGCF_000007785#EF_RS05770Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1008540

Simplified PFAM architecture for HKOC_1008540

PFAM domain coverage: 424 / 609 aa (69.6%)

1 aa609 aa
Cache_WalK: 79-164 aaCache_WalKHAMP: 197-249 aaHAMPPAS: 260-366 aaPASHisKA: 376-442 aaHisKAHATPase_c: 491-601 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[79-164] | HAMP[197-249] | PAS[260-366] | HisKA[376-442] | HATPase_c[491-601]
  • Domain count: 5
  • Matched identifier: HKOC_1008540
  • Positioned domains: Cache_WalK 79-164 ; HAMP 197-249 ; PAS 260-366 ; HisKA 376-442 ; HATPase_c 491-601
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007785#EF_RS05770

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 491 075 · GCF_000160155
AssemblyASM16015v1 · Scaffoldhaploid
Genome composition3 129 930 bp · 37,0% GCEnterococcus faecalis EnGen0297
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key